Evidence map›Paper›PMID 36834533›Full record

ArticleInternational journal of molecular sciences2023

Orthodontic Compression Enhances Macrophage M2 Polarization via Histone H3 Hyperacetylation.

Yao Wang, Sabine Groeger, Jiawen Yong, Sabine Ruf

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. The Role of Cytokines in Orthodontic Tooth Movement.International journal of molecular sciences · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Yao WangDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-7432-2614
Sabine GroegerDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.
Jiawen YongDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-3021-075X
Sabine RufDepartment of Orthodontics, Faculty of Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.ORCID 0000-0002-6193-1314
Justus-Liebig-Universität Gießen · DE

Funding

China Scholarship Council 202208080301
6 · The paper itself

Abstract

Orthodontic tooth movement is a complex periodontal remodeling process triggered by compression that involves sterile inflammation and immune responses. Macrophages are mechanically sensitive immune cells, but their role in orthodontic tooth movement is unclear. Here, we hypothesize that orthodontic force can activate macrophages, and their activation may be associated with orthodontic root resorption. After force-loading and/or adiponectin application, the migration function of macrophages was tested via scratch assay, and

Indexed as

HistonesRoot ResorptionCulture Media, ConditionedHumansInterleukin-10Ion ChannelsMacrophagesCulture Media, ConditionedHistonesInterleukin-10Ion ChannelsPIEZO1 protein, humanacetylationadiponectincompressive forceH3 histonemacrophagespolarization

Identifiers

PMID36834533
PMCPMC9958841
OpenAlexW4319318056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.