Evidence map›Paper›PMID 36834385›Full record

ArticleInternational journal of environmental research and public health2023

The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy.

Fernando Vázquez-Sánchez, María Del Carmen Lloria-Gil, Ana Isabel Gómez-Menéndez, Francisco Isidro-Mesas, Ana Echavarría-Íñiguez, Javier Martín-Alonso, Jerónimo González-Bernal, Josefa González-Santos, Anna Berardi, Marco Tofani and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Degenerative cervical myelopathy diagnosis: applicability of artificial intelligence-enhanced modalities in a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Fernando Vázquez-SánchezNeurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain.ORCID 0000-0003-1197-0195
María Del Carmen Lloria-GilNeurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain.
Ana Isabel Gómez-MenéndezNeurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain.ORCID 0000-0003-3869-9569
Francisco Isidro-MesasNeurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain.
Ana Echavarría-ÍñiguezNeurology Department, Valladolid Clinical University Hospital, 47003 Valladolid, Spain.
Javier Martín-AlonsoNeurosurgery Department, Burgos University Hospital, 09006 Burgos, Spain.
Jerónimo González-BernalDepartment of Health Sciences, Burgos University, 09001 Burgos, Spain.ORCID 0000-0002-7298-9060
Josefa González-SantosDepartment of Health Sciences, Burgos University, 09001 Burgos, Spain.
Anna BerardiDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-0670-5303
Marco TofaniDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-2071-4513
Giovanni GaleotoDepartment of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9043-5686
Beatriz García-LópezNeurophysiology Department, Burgos University Hospital, 09006 Burgos, Spain.ORCID 0000-0003-1364-2603
Universidad de Burgos · ESSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative cervical myelopathy (DCM) consists of spinal cord damage due to its compression through the cervical spine. The leading cause is degenerative. The diagnosis is clinical, and the therapeutic approach is usually surgical. Confirmation of the diagnostic suspicion is done by magnetic resonance imaging (MRI); however, this test lacks functional information of the spinal cord, the abnormality of which may precede involvement in neuroimaging. Neurophysiological examination using somatosensory evoked potentials (SSEPs) and transcranial magnetic stimulation (TMS) allows for an evaluation of spinal cord function, and provides information in the diagnostic process. Its role in the post-surgical follow-up of patients undergoing decompressive surgery is being studied. We present a retrospective study of 24 patients with DCM and surgical decompression who underwent neurophysiological tests (TMS and SSEP) before, 6, and 12 months after surgery. The result of the TMS and the SSEP in the post-operative follow-up did not correlate with the clinical outcome, either subjective or measured by clinical scales at six months. We only found post-surgical improvement of central conduction times (CMCTs) in patients with severe pre-surgical motor impairment on TMS. In patients with normal pre-surgical CMCT, we found a transient worsening with return to baseline at the one-year follow-up. Most patients presented pre-surgical increased P40 latency at diagnosis. CMCT and SSEP were more related to clinical outcomes one year after the surgical procedure and were very useful in diagnosing.

Indexed as

Spinal Cord CompressionSpinal Cord DiseasesCervical VertebraeCME-CarbodiimideEvoked Potentials, MotorFollow-Up StudiesHumansMagnetic Resonance ImagingRetrospective Studies1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimideCME-Carbodiimidecervical spondylotic myelopathymyelopathyspinal cord

Identifiers

PMID36834385
PMCPMC9959727
OpenAlexW4321374227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.