Trial reportInternational journal of environmental research and public health2023
The Effect of Calcium Hydroxide, Triple Antibiotic Paste and Chlorhexidine on Pain in Teeth with Symptomatic Apical Periodontitis: A Randomised Controlled Trial.
Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Efficacy of Novel Jasminum-based Nano-reinforced Calcium Hydroxide Medicament on Postoperative Pain: a Triple-blind Study
Comparison of Different Intracanal Medicaments on Post-operative Pain in Teeth With Symptomatic Apical Periodontitis: A Randomised Controlled Trial
Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Clinical and radiographic success of lesion sterilization and tissue repair in primary teeth: a systematic review and meta-analysis.The Saudi dental journal · 2025Article
- The Effectiveness of Different Intracanal Medicaments in Treating Apical Periodontitis.Journal of pharmacy & bioallied sciences · 2025Article
- Comparative Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, and Calcium Hydroxide with 2% Chlorhexidine as Intracanal Medicaments in Reducing Interappointment Pain during Endodontic Treatment: AnInternational journal of clinical pediatric dentistry · 2025Article
- Root Canal Dentin Microhardness after Contact with Antibiotic Medications: An In Vitro Study.Dentistry journal · 2024Article
- Endodontic infection control practices among Pakistani general dental practitioners: A national cross-sectional questionnaire survey.Journal of Taibah University Medical Sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne of the main reasons for post endodontic pain is the polymicrobial intracanal flora that may survive the initial disinfection. A single antimicrobial agent might not provide adequate disinfection, and an antimicrobial combination such as triple antibiotic paste was tested to achieve this goal.
aimThe study aimed to assess the efficacy of three intra-canal medicaments on post root canal preparation pain. MATERIALS AND
methodsEighty patients with single-rooted necrotic teeth and symptomatic apical periodontitis were randomly assigned to four treatment groups (
resultsTukey's post hoc test revealed significantly lower pain scores in Group 3 compared with other groups at all follow up intervals. Dunnett's test showed significantly lower pain in Group 3 compared with the Control group at 48, 72 and 96 hrs, postoperatively.
conclusionsTriple-antibiotic paste showed effective pain control as an intracanal medication on necrotic teeth with symptomatic apical periodontitis.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.