Evidence map›Paper›PMID 36833382›Full record

ArticleGenes2023

Association of

Kainat Arshad, Uzma Ishfaq, Muhammad Asif, Atif Akbar, Kehkashan Fatima Pitafi, Muhammad Rehan Mulghani, Uzman Shaheen, Suleman Saeed, Muhammad Arif, Ahsan Bashir and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Kainat ArshadDepartment of Zoology, Ghazi University, Dera Ghazi Khan 32200, Pakistan.
Uzma IshfaqInstitute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan.
Muhammad AsifInstitute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan 60800, Pakistan.
Atif AkbarDepartment of Statistics, Bahauddin Zakariya University, Multan 60800, Pakistan.
Kehkashan Fatima PitafiSenior Registrar Medicine, Teaching Hospital, Dera Ghazi Khan 32200, Pakistan.
Muhammad Rehan MulghaniSenior Registrar Medicine, Teaching Hospital, Dera Ghazi Khan 32200, Pakistan.
Uzman ShaheenPathology Department, Dera Ghazi Khan Medical College, Dera Ghazi Khan 32200, Pakistan.
Suleman SaeedDepartment of Zoology, Ghazi University, Dera Ghazi Khan 32200, Pakistan.ORCID 0000-0001-5962-473X
Muhammad ArifDepartment of Zoology, Ghazi University, Dera Ghazi Khan 32200, Pakistan.
Ahsan BashirDepartment of Zoology, Ghazi University, Dera Ghazi Khan 32200, Pakistan.ORCID 0000-0002-4588-7472
Muhammad FarooqDepartment of Zoology, Ghazi University, Dera Ghazi Khan 32200, Pakistan.ORCID 0000-0001-5932-1982
Alan Henry BrookDental School, University of Adelaide, Adelaide 5005, Australia.
Furhan IqbalInstitute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan.ORCID 0000-0003-4996-0152
Ghazi University · PKBahauddin Zakariya University · PKThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic periodontal disease (CP) is a multifactorial infectious and inflammatory disease that occurs due to the challenge between the immune response of the host and specific periodontal bacteria, and that can lead to tooth loss due to damage inflicted to the supporting tissue. The current study investigates the genotypes of the

methodsA total of 203 clinically confirmed CP patients and 201 control subjects were enrolled from Multan and Dera Ghazi Khan Districts in Pakistan from April to July 2022. Multiplex Polymerase Chain Reaction (PCR) and tetra-primer amplification refractory mutation system-polymerase chain reaction (T-ARMS-PCR) approaches were applied to determine the genotypes of the studied GSTs. The association of rs1695 in

resultsThe absence of

conclusionOur results indicate that the genotypes of the analyzed GSTs affect the levels of protection from oxidative stress and may therefore influence the disease progression in CP.

Indexed as

Genetic Predisposition to DiseaseGlutathione TransferasePeriodontal DiseasesAdolescentAdultChildGlutathione S-Transferase piHumansMultiplex Polymerase Chain ReactionPakistanPolymorphism, Single NucleotideRisk FactorsYoung AdultGlutathione S-Transferase piglutathione S-transferase T1Glutathione TransferaseGSTP1 protein, humanchronic periodontitisGSTM1GSTP1GSTT1rs1695

Identifiers

PMID36833382
PMCPMC9957474
OpenAlexW4319985816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.