Evidence map›Paper›PMID 36833368›Full record

ArticleGenes2023

Serum MicroRNAs as Predictors for HCV Progression and Response to Treatment in Pakistani Patients.

Sadia Manzoor, Imran Riaz Malik, Shah Jahan, Muhammad Bilal Sarwar, Asma Bashir, Sulaiman Shams, Abrar Hussain

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Sadia ManzoorDepartment of Biotechnology, University of Sargodha, Sargodha 40100, Pakistan.
Imran Riaz MalikDepartment of Biotechnology, University of Sargodha, Sargodha 40100, Pakistan.
Shah JahanDepartment of Immunology, University of Health Sciences, Lahore 54700, Pakistan.ORCID 0000-0002-1730-5025
Muhammad Bilal SarwarFood and Biotechnology Research Center, PCSIR Laboratories Complex Lahore, Lahore 54700, Pakistan.ORCID 0000-0003-0083-2248
Asma BashirDepartment of Biosciences, Faculty of Life Sciences, Shaheed Zulfikar Ali Bhutto Institute of Science and Technology (SZABIST), Karachi 75600, Pakistan.ORCID 0000-0002-0912-9199
Sulaiman ShamsDepartment of Biochemistry, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.ORCID 0000-0001-7792-1180
Abrar HussainFaculty of Life Sciences and Informatics, BUITEMS, Quetta 87300, Pakistan.ORCID 0000-0002-7646-5643
University of Sargodha · PKAbdul Wali Khan University Mardan · PKBalochistan University of Information Technology, Engineering and Management Sciences · PKPakistan Council of Scientific & Industrial Research · PKShaheed Zulfiqar Ali Bhutto Institute of Science and Technology · PKUniversity of Health Sciences Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis is one of the common liver diseases, imposing a heavy health burden worldwide. Acute hepatitis may develop into chronic hepatitis, progressing to cirrhosis and hepatocellular carcinoma. In the present study, the expression of miRNAs was quantified by real-time PCR, such as miRNA-182, 122, 21, 150, 199, and 222. Along with the control group, HCV was divided into chronic, cirrhosis, and HCC groups. The treated group was also included after the successful treatment of HCV. Biochemical parameters, such as ALT, AST, ALP, bilirubin, viral load, and AFP (HCC), were also evaluated in all of the study groups. We compared the control and diseased groups; these parameters showed significant results (

Indexed as

Carcinoma, HepatocellularHepatitis CLiver NeoplasmsMicroRNAsHumansLiver CirrhosisPakistanMicroRNAsMIR150, humanMirn182 microRNA, humanbiomarkerchroniccirrhosisHCChepatitis Ctreatment

Identifiers

PMID36833368
PMCPMC9957303
OpenAlexW4319786189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.