Evidence map›Paper›PMID 36833314›Full record

ArticleGenes2023

KEGG_Extractor: An Effective Extraction Tool for KEGG Orthologs.

Chao Zhang, Zhongwei Chen, Miming Zhang, Shulei Jia

Abstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chao ZhangMarine Sustainable Development Research Center, Third Institute of Oceanography, Xiamen 361102, China.
Zhongwei ChenNantong Marine Environmental Monitoring Center, Ministry of Natural Resources, Nantong 226002, China.
Miming ZhangThird Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, China.
Shulei JiaInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0003-2483-0300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The KEGG Orthology (KO) database is a widely used molecular function reference database which can be used to conduct functional annotation of most microorganisms. At present, there are many KEGG tools based on the KO entries for annotating functional orthologs. However, determining how to efficiently extract and sort the annotation results of KEGG still hinders the subsequent genome analysis. There is a lack of effective measures used to quickly extract and classify the gene sequences and species information of the KEGG annotations. Here, we present a supporting tool: KEGG_Extractor for species-specific genes extraction and classification, which can output the results through an iterative keyword matching algorithm. It can not only extract and classify the amino acid sequences, but also the nucleotide sequences, and it has proved to be fast and efficient for microbial analysis. Analysis of the ancient Wood Ljungdahl (WL) pathway through the KEGG_Extractor reveals that ~226 archaeal strains contained the WL pathway-related genes. Most of them were

Indexed as

GenomeAmino Acid SequenceBase SequenceDatabases, FactualKEGGKEGG Orthology (KO)keyword matchingmethodology

Identifiers

PMID36833314
PMCPMC9956942

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.