Evidence map›Paper›PMID 36833294›Full record

ArticleGenes2023

Association between the rs820218 Variant within the

Rui Sergio Monteiro de Barros, Carla de Castro Sant' Anna, Diego Di Felipe Ávila Alcantara, Karla Beatriz Cardias Cereja Pantoja, Marianne Rodrigues Fernandes, Lívia Guerreiro de Barros Bentes, Antônio Leonardo Jatahi Cavalcanti Pimentel, Rafael Silva Lemos, Nyara Rodrigues Conde de Almeida, Manuela Rodrigues Neiva Fernandes and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rui Sergio Monteiro de BarrosHospital Ophir Loyola, Belém 66063-240, Brazil.
Carla de Castro Sant' AnnaHospital Ophir Loyola, Belém 66063-240, Brazil.ORCID 0000-0002-7171-7071
Diego Di Felipe Ávila AlcantaraHospital Ophir Loyola, Belém 66063-240, Brazil.
Karla Beatriz Cardias Cereja PantojaNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.ORCID 0000-0002-1278-3722
Marianne Rodrigues FernandesNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.ORCID 0000-0002-1396-3442
Lívia Guerreiro de Barros BentesCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Antônio Leonardo Jatahi Cavalcanti PimentelCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.ORCID 0000-0002-1226-5394
Rafael Silva LemosCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Nyara Rodrigues Conde de AlmeidaCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Manuela Rodrigues Neiva FernandesCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Thiago Sequeira da CruzCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Atylla de Andrade CandidoCentro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém 66087-662, Brazil.
Rommel Mario Rodriguez BurbanoHospital Ophir Loyola, Belém 66063-240, Brazil.ORCID 0000-0002-4872-234X
Universidade do Estado do Pará · BRUniversidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRotator cuff disease is one of the leading causes of musculoskeletal pain and disability, and its etiology is most likely multifactorial but remains incompletely understood. Therefore, the objective of this research was to investigate the relationship of the single-nucleotide rs820218 polymorphism of the SAP30-binding protein (SAP30BP) gene with rotator cuff tears in the Amazonian population.

methodsThe case group consisted of patients who were operated on due to rotator cuff tears in a hospital in the Amazon region between 2010 and 2021, and the control group was composed of individuals who were selected after negative physical examinations for rotator cuff tears. Genomic DNA was obtained from saliva samples. For the genotyping and allelic discrimination of the selected single nucleotide polymorphism (rs820218) in the

resultsThe frequency of the A allele in the control group was four times as high as that in the case group (AA homozygotes); an association of the genetic variant rs820218 of the

conclusionsThe presence of the A allele indicates protection against rotator cuff tears.

Indexed as

Rotator Cuff InjuriesTranscription FactorsAllelesGene FrequencyHumansNuclear ProteinsPolymorphism, Single NucleotideRotator CuffNuclear ProteinsSAP30BP protein, humanTranscription FactorsAmazonian populationgenetic susceptibilityrotator cuff tearsrs820218SAP30BPsingle-nucleotide polymorphism

Identifiers

PMID36833294
PMCPMC9957240
OpenAlexW4318594442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.