Evidence map›Paper›PMID 36833279›Full record

ReviewGenes2023

The Genetic Side of the Mood: A Scientometric Review of the Genetic Basis of Mood Disorders.

Giovanni Bonacina, Alessandro Carollo, Gianluca Esposito

Abstract readReview
In one paragraph

Review in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Circulating long noncoding RNA: New frontiers in biomarker research for mood disorders.Genomic psychiatry : advancing science from genes to society · 2025
    Article
  4. Review
  5. Correlation of theFrontiers in pharmacology · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giovanni BonacinaDepartment of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy.ORCID 0000-0003-1608-4272
Alessandro CarolloDepartment of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy.ORCID 0000-0002-2737-0218
Gianluca EspositoDepartment of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy.ORCID 0000-0002-9442-0254

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mood disorders are highly heritable psychiatric disorders. Over the years, many genetic polymorphisms have been identified to pose a higher risk for the development of mood disorders. To overview the literature on the genetics of mood disorders, a scientometric analysis was performed on a sample of 5342 documents downloaded from Scopus. The most active countries and the most impactful documents in the field were identified. Furthermore, a total of 13 main thematic clusters emerged in the literature. From the qualitative inspection of clusters, it emerged that the research interest moved from a monogenic to a polygenic risk framework. Researchers have moved from the study of single genes in the early 1990s to conducting genome-wide association studies around 2015. In this way, genetic overlaps between mood disorders and other psychiatric conditions emerged too. Furthermore, around the 2010s, the interaction between genes and environmental factors emerged as pivotal in understanding the risk for mood disorders. The inspection of thematic clusters provides a valuable insight into the past and recent trends of research in the genetics of mood disorders and sheds light onto future lines of research.

Indexed as

Biomedical ResearchMood DisordersBibliometricsGenome-Wide Association StudyHumansPolymorphism, Geneticaffective disordersbibliometricsdocument co-citation analysisgeneticsmood disordersscientometrics

Identifiers

PMID36833279
PMCPMC9956267

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.