Evidence map›Paper›PMID 36833045›Full record

ArticleHealthcare (Basel, Switzerland)2023

Contrast-Enhanced Spectral Mammography in the Evaluation of Breast Microcalcifications: Controversies and Diagnostic Management.

Luca Nicosia, Anna Carla Bozzini, Giulia Signorelli, Simone Palma, Filippo Pesapane, Samuele Frassoni, Vincenzo Bagnardi, Maria Pizzamiglio, Mariagiorgia Farina, Chiara Trentin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Luca NicosiaBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-3979-8075
Anna Carla BozziniBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Giulia SignorelliBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Simone PalmaDepartment of Diagnostic Imaging, Radiation Oncology and Hematology, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8824-2535
Filippo PesapaneBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-0374-5054
Samuele FrassoniDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-4265-2627
Vincenzo BagnardiDepartment of Statistics and Quantitative Methods, University of Milan-Bicocca, 20126 Milan, Italy.
Maria PizzamiglioBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Mariagiorgia FarinaBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Chiara TrentinBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Silvia PencoBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Lorenza MeneghettiBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Claudia SangalliData Management, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-3437-8939
Enrico CassanoBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
European Institute of Oncology · ITUniversity of Milano-Bicocca · ITAgostino Gemelli University Polyclinic · ITData Management (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the diagnostic performance of contrast-enhanced spectral mammography (CESM) in predicting breast lesion malignancy due to microcalcifications compared to lesions that present with other radiological findings. Three hundred and twenty-one patients with 377 breast lesions that underwent CESM and histological assessment were included. All the lesions were scored using a 4-point qualitative scale according to the degree of contrast enhancement at the CESM examination. The histological results were considered the gold standard. In the first analysis, enhancement degree scores of 2 and 3 were considered predictive of malignity. The sensitivity (SE) and positive predictive value (PPV) were significative lower for patients with lesions with microcalcifications without other radiological findings (SE = 53.3% vs. 82.2%,

Indexed as

breast biopsybreast cancerCESMmicrocalcifications

Identifiers

PMID36833045
PMCPMC9956946
OpenAlexW4319787234

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.