Evidence map›Paper›PMID 36832810›Full record

ArticleFoods (Basel, Switzerland)2023

Oral Administration of Lotus-Seed Resistant Starch Protects against Food Allergy.

Jiamiao Hu, Zhongjing Lin, Lanxin Li, Baodong Zheng, Hongliang Zeng, Yanbo Wang, Yi Zhang

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiamiao HuCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0001-6489-9877
Zhongjing LinCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0003-2982-0283
Lanxin LiCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Baodong ZhengCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0003-3133-1219
Hongliang ZengCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0002-9426-8133
Yanbo WangSchool of Food and Health, Beijing Technology and Business University, Beijing 102448, China.
Yi ZhangCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0002-6837-4258
Fujian Agriculture and Forestry University · CNBeijing Technology and Business University · CN

Funding

Fujian Province Science and Technology Innovation Leading Talent Project KRC16002ANational High-Level Talents Special Support Program KRC19007A
6 · The paper itself

Abstract

Food allergy is a serious food safety and public health issue. However, the medical interventions for allergy treatment are still suboptimal. Recently, the gut microbiome-immune axis has been considered as a promising target to reduce the symptoms of food allergy. In this study, we explore the oral administration of lotus-seed resistant starch as a means to protect against food allergy using an ovalbumin (OVA) sensitization and challenge rodent model. The results obtained showed that lotus-seed resistant starch intervention alleviated the food allergy symptoms (such as reductions in body temperature and allergic diarrhea). Furthermore, lotus-seed resistant starch also attenuated the increase in OVA-specific immunoglobulins and improved Th1/Th2 imbalance in OVA-sensitized mice. These anti-allergic effects might be associated with the actions of lotus-seed resistant starch on intestinal microbiota. Taken together, our findings suggest that daily ingestion of lotus-seed resistant starch might be effective for the alleviation of food allergy.

Indexed as

food allergylotus seedresistant starchTh1/Th2 balance

Identifiers

PMID36832810
PMCPMC9956242
OpenAlexW4319594882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.