Evidence map›Paper›PMID 36832479›Full record

ArticleChildren (Basel, Switzerland)2023

Masked Randomized Trial of Epinephrine versus Vasopressin in an Ovine Model of Perinatal Cardiac Arrest.

Munmun Rawat, Sylvia Gugino, Carmon Koenigsknecht, Justin Helman, Lori Nielsen, Deepika Sankaran, Jayasree Nair, Praveen Chandrasekharan, Satyan Lakshminrusimha

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Munmun RawatDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.ORCID 0000-0001-9703-9857
Sylvia GuginoDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.
Carmon KoenigsknechtDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.
Justin HelmanDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.
Lori NielsenDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.
Deepika SankaranDepartment of Pediatrics, UC Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0002-6704-6949
Jayasree NairDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.
Praveen ChandrasekharanDepartment of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA.ORCID 0000-0001-8727-3017
Satyan LakshminrusimhaDepartment of Pediatrics, UC Davis Medical Center, Sacramento, CA 95817, USA.ORCID 0000-0001-6098-2155
University at Buffalo, State University of New York · USUniversity of California Davis Medical Center · US

Funding

Optimizing Chest Compressions for Bradycardia during Neonatal ResuscitationR01HD104909 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHANDRASEKHARAN, PRAVEEN · 2021 to 2025
$1.5M
Optimal Inspired Oxygen during Chest Compressions in Neonatal ResuscitationR03HD104062 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RAWAT, MUNMUN · 2021 to 2022
$160k
NICHD NIH HHS R01 HD104909NICHD NIH HHS R03 HD104062
6 · The paper itself

Abstract

backgroundCurrent neonatal resuscitation guidelines recommend the use of epinephrine for bradycardia/arrest not responding to ventilation and chest compressions. Vasopressin is a systemic vasoconstrictor and is more effective than epinephrine in postnatal piglets with cardiac arrest. There are no studies comparing vasopressin with epinephrine in newly born animal models with cardiac arrest induced by umbilical cord occlusion.

Indexed as

epinephrineresuscitationvasopressin

Identifiers

PMID36832479
PMCPMC9955402
OpenAlexW4319921250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.