Evidence map›Paper›PMID 36832475›Full record

ArticleChildren (Basel, Switzerland)2023

Influence of Perinatal Factors on Blood Tryptase and Fecal Calprotectin Levels in Newborns.

Justine Paysal, Charlotte Oris, Ugo Troin, Pierre-Nicolas Limeri, Jeanne Allard, Marie Tadrent, Bruno Pereira, Etienne Merlin, Emmanuelle Rochette, Bertrand Evrard and 3 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Justine PaysalCHU Clermont-Ferrand, Néonatologie et Réanimation Pédiatrique, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-3303-7980
Charlotte OrisCHU Clermont-Ferrand Gabriel Montpied, Biochimie, F-63000 Clermont-Ferrand, France.
Ugo TroinINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Pierre-Nicolas LimeriINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Jeanne AllardINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Marie TadrentINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Bruno PereiraCHU Clermont-Ferrand, Direction de la Recherche Clinique et de l'Innovation, Secteur Biométrie et Médico-économi, F-63000 Clermont-Ferrand, France.ORCID 0000-0003-3778-7161
Etienne MerlinINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.
Emmanuelle RochetteINSERM, CIC 1405, CRECHE Unit, CHU Clermont-Ferrand, F-63000 Clermont-Ferrand, France.ORCID 0000-0001-5180-9916
Bertrand EvrardCHU Clermont-Ferrand, Immunologie, F-63000 Clermont-Ferrand, France.
Julie DurifCHU Clermont-Ferrand Gabriel Montpied, Biochimie, F-63000 Clermont-Ferrand, France.
Vincent SapinCHU Clermont-Ferrand Gabriel Montpied, Biochimie, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-7452-315X
Maguelonne PonsCHU Clermont-Ferrand, Chirurgie Pédiatrique, F-63000 Clermont-Ferrand, France.
Inserm · FRCentre Hospitalier Universitaire de Clermont-Ferrand · FR

Funding

CHU Clermont Ferrand Pons-AOI-2021
6 · The paper itself

Abstract

backgroundBlood tryptase and fecal calprotectin levels may serve as biomarkers of necrotizing enterocolitis. However, their interpretation may be hindered by the little-known effects of perinatal factors. The aim of this study was to compare the tryptase and calprotectin levels in newborns according to their term, trophicity, and sex.

methodOne hundred and fifty-seven premature newborns and 157 full-term newborns were included. Blood tryptase and fecal calprotectin were assayed.

resultsBlood tryptase levels were higher in premature than in full-term newborns (6.4 vs. 5.2 µg/L;

conclusionsThe differences in tryptase levels according to term could be linked to early aggression of the still-immature digestive wall in premature newborns, in particular, by enteral feeding started early. The unexpected influence of sex on fecal calprotectin levels remains unexplained.

Indexed as

blood tryptasefecal calprotectinnewbornsperinatal factors

Identifiers

PMID36832475
PMCPMC9954950
OpenAlexW4319967380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.