Evidence map›Paper›PMID 36832324›Full record

ArticleChildren (Basel, Switzerland)2023

Monitoring of Auditory Function in Newborns of Women Infected by SARS-CoV-2 during Pregnancy.

Enrico Apa, Maria Teresa Presutti, Cecilia Rossi, Maria Federica Roversi, Salvatore Neri, Giancarlo Gargano, Giovanni Bianchin, Valeria Polizzi, Valeria Caragli, Daniele Monzani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Enrico ApaOtorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.ORCID 0000-0003-0688-5770
Maria Teresa PresuttiInfectious Disease Unit, Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, University of Bologna, 40100 Bologna, Italy.
Cecilia RossiNeonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.
Maria Federica RoversiNeonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.
Salvatore NeriNeonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.
Giancarlo GarganoDepartment of Obstetrics and Paediatrics, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42121 Reggio Emilia, Italy.
Giovanni BianchinDepartment of Audiology, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42123 Reggio Emilia, Italy.
Valeria PolizziDepartment of Audiology, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42123 Reggio Emilia, Italy.
Valeria CaragliOtorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.
Daniele MonzaniENT, Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, University of Verona, Borgo Roma Hospital, 37100 Verona, Italy.
Alberto BerardiNeonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.ORCID 0000-0002-3534-7499
Silvia PalmaAudiology, Primary Care Department; AUSL of Modena, 41100 Modena, Italy.ORCID 0000-0002-5521-4343
Elisabetta GenoveseOtorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy.
Azienda Ospedaliero-Universitaria di Modena · ITSanta Maria Nuova Hospital · ITAzienda Unita' Sanitaria Locale Di Modena · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational SARS-CoV-2 infection can impact maternal and neonatal health. The virus has also been reported to cause newborn sensorineural hearing loss, but its consequences for the auditory system are not fully understood.

objectiveThe aim of this study was to evaluate the impact of maternal SARS-CoV-2 infection during pregnancy on newborn' hearing function during the first year of life.

methodsAn observational study was conducted from 1 November 2020 to 30 November 2021 at University Modena Hospital. All newborns whose mother had been infected by SARS-CoV-2 during pregnancy were enrolled and underwent audiological evaluation at birth and at 1 year of age.

resultsA total of 119 neonates were born from mothers infected by SARS-CoV-2 during pregnancy. At birth, five newborns (4.2%) presented an increased threshold of ABR (Auditory Brainstem Evoked Response), but the results were confirmed only in 1.6% of cases, when repeated 1 month later, while the ABR thresholds in all other children returned to normal limits. At the 1-year follow-up, no cases of moderate or severe hearing loss were observed, while concomitant disorders of the middle ear were frequently observed.

conclusionsMaternal SARS-CoV-2 infection, regardless of the trimester in which it was contracted, appears not to induce moderate or severe hearing loss in infants. It is important to clarify the possible effect of the virus on late-onset hearing loss and future research is needed.

Indexed as

Auditory Brainstem Evoked Responsechildrenhealthcare policyhearing lossSARS-CoV-2

Identifiers

PMID36832324
PMCPMC9954415
OpenAlexW4317620415

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.