Evidence map›Paper›PMID 36832159›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Challenging Patterns of Atypical Dermatofibromas and Promising Diagnostic Tools for Differential Diagnosis of Malignant Lesions.

Olguța Anca Orzan, Alexandra Maria Dorobanțu, Cristian Dorin Gurău, Sibel Ali, Mara Mădălina Mihai, Liliana Gabriela Popa, Călin Giurcăneanu, Irina Tudose, Beatrice Bălăceanu

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Dermatofibroma: Reappraisal and Updated Review.Clinical, cosmetic and investigational dermatology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Olguța Anca OrzanDermatology Department, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Alexandra Maria DorobanțuDermatology Department, "Elias" University Emergency Hospital, 011461 Bucharest, Romania.ORCID 0000-0002-7752-7930
Cristian Dorin GurăuOrthopedy and Traumatology Clinic, Clinical Emergency Hospital, 014451 Bucharest, Romania.
Sibel AliDermatology Department, "Elias" University Emergency Hospital, 011461 Bucharest, Romania.ORCID 0000-0002-1488-659X
Mara Mădălina MihaiDermatology Department, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-1436-0088
Liliana Gabriela PopaDermatology Department, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Călin GiurcăneanuDermatology Department, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Irina TudoseAnatomic Pathology Laboratory, "Elias" University Emergency Hospital, 011461 Bucharest, Romania.
Beatrice BălăceanuDermatology Department, "Elias" University Emergency Hospital, 011461 Bucharest, Romania.
Clinical Emergency Hospital Bucharest · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatofibroma (DF) or fibrous histiocytoma is one of the most frequent benign cutaneous soft-tissue lesions, characterized by a post-inflammatory tissue reaction associated with fibrosis of the dermis. Clinically DFs have a polymorphous clinical aspect from the solitary, firm, single nodules to multiple papules with a relatively smooth surface. However, multiple atypical clinicopathological variants of DFs have been reported and, therefore, clinical recognition may become challenging, leading to a more burdensome identification and sometimes to misdiagnosis. Dermoscopy is considered an important tool in DFs diagnosis, as it improves diagnostic accuracy for clinically amelanotic nodules. Although typical dermoscopic patterns are most frequently seen in clinical practice, there have also been some atypical variants described, mimicking some underlying recurrent and sometimes harmful skin afflictions. Usually, no treatment is required, although an appropriate work-up may be necessary in specific cases, such as in the presence of atypical variants or a history of recent changes. This narrative review's aim is to summarize current evidence regarding clinical presentation, positive and differential diagnosis of atypical dermatofibromas and also to raise awareness about the importance of specific characteristics of atypical variants to better differentiate them from malignant conditions.

Indexed as

atypical fibrous histiocytomabenign cutaneous tumoursdermatofibromadermoscopy

Identifiers

PMID36832159
PMCPMC9955442
OpenAlexW4320497497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.