Evidence map›Paper›PMID 36832064›Full record

ReviewBiosensors2023

Review of HIV Self Testing Technologies and Promising Approaches for the Next Generation.

Amanda Bacon, Weijing Wang, Hankeun Lee, Saurabh Umrao, Prima Dewi Sinawang, Demir Akin, Kodchakorn Khemtonglang, Anqi Tan, Sabina Hirshfield, Utkan Demirci and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Self-swabbing versus assisted swabbing for viral detection by qRT-PCR: the experience from SARS-CoV-2 based on a meta-analysis of six prospectively designed evaluations conducted in a UK setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Amanda BaconDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Weijing WangDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7460-7735
Hankeun LeeNick Holonyak Jr. Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-9332-3989
Saurabh UmraoNick Holonyak Jr. Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Prima Dewi SinawangCenter at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.ORCID 0000-0001-8460-3260
Demir AkinCenter at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Kodchakorn KhemtonglangDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0003-4106-0790
Anqi TanDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sabina HirshfieldSpecial Treatment and Research (STAR) Program, Department of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, NY 11203, USA.ORCID 0000-0002-2649-469X
Utkan DemirciCenter at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA 94304, USA.
Xing WangDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-9930-3287
Brian T CunninghamDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-9681-2104
University of Illinois Urbana-Champaign · USStanford University · USSUNY Downstate Health Sciences University · US

Funding

The Center for Label-free Imagingand Multiscale Biophotonics (CLIMB)P41EB031772 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Stephen A Boppart · 2022 to 2026
$7.6M
Supporting Treatment Adherence For Resilience and Thriving (START): A MHealth Intervention to Improve ART Adherence For HIV-Positive Stimulant Using Men - Diversity SupplementR01DA049843 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRICO, ADAM WAYNE · 2019 to 2023
$3.9M
Ultrasensitive HIV viral load quantitation using designer DNA nanostructure capture probes and photonic resonator interference scattering microscopyR01AI159454 · NIAID · STANFORD UNIVERSITY · PI CUNNINGHAM, BRIAN T., DEMIRCI, UTKAN · 2021 to 2025
$3.6M
Scale-up of an Internet-Delivered Randomized Controlled Trial for HIV+ MenR01MH100973 · NIMH · PUBLIC HEALTH SOLUTIONS · PI HIRSHFIELD, SABINA · 2014 to 2016
$1.9M
Smartphone-linked system for diagnosis and epidemiological reporting of pathogens at the point of careR01AI139401 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, CUNNINGHAM, BRIAN T. · 2019 to 2022
$1.7M
Portable Nanostructured Photonic Crystal Device for HIV-1 Viral LoadR01AI120683 · NIAID · STANFORD UNIVERSITY · PI CUNNINGHAM, BRIAN T., DEMIRCI, UTKAN · 2016 to 2019
$1.5M
Detection and Automatic Privacy-Protected Contact Tracing System Designed for COVID-19U01AA029348 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PENG, LU, WANG, XING · 2021 to 2023
$1.4M
A Rapid and Sensitive Technology for Direct Sensing of Intact SARS-CoV-2 Virions Using Designer DNA Nanostructure Probes and a Smartphone FluorimeterR21EB031310 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CUNNINGHAM, BRIAN T., WANG, XING · 2021 to 2021
$422k
NIAAA NIH HHS U01 AA029348NIAID NIH HHS R01 AI120683NIAID NIH HHS R01 AI139401NIAID NIH HHS R01 AI159454NIBIB NIH HHS P41 EB031772NIBIB NIH HHS R21 EB031310NIDA NIH HHS R01 DA049843NIH HHS R01AI159454NIH HHS R01DA049843NIH HHS R01MH100973NIH HHS R21EB031310NIMH NIH HHS R01 MH100973
6 · The paper itself

Abstract

The ability to self-test for HIV is vital to preventing transmission, particularly when used in concert with HIV biomedical prevention modalities, such as pre-exposure prophylaxis (PrEP). In this paper, we review recent developments in HIV self-testing and self-sampling methods, and the potential future impact of novel materials and methods that emerged through efforts to develop more effective point-of-care (POC) SARS-CoV-2 diagnostics. We address the gaps in existing HIV self-testing technologies, where improvements in test sensitivity, sample-to-answer time, simplicity, and cost are needed to enhance diagnostic accuracy and widespread accessibility. We discuss potential paths toward the next generation of HIV self-testing through sample collection materials, biosensing assay techniques, and miniaturized instrumentation. We discuss the implications for other applications, such as self-monitoring of HIV viral load and other infectious diseases.

Indexed as

COVID-19HIV InfectionsHumansPoint-of-Care TestingSARS-CoV-2Self-TestingbiosensorHIV self-testingHIV viral loadLFAviral testing

Identifiers

PMID36832064
PMCPMC9954708
OpenAlexW4321373135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.