Evidence map›Paper›PMID 36832045›Full record

ArticleBiosensors2023

A Multiple-Array SPRi Biosensor as a Tool for Detection of Gynecological-Oncological Diseases.

Beata Szymanska, Zenon Lukaszewski, Kinga Hermanowicz-Szamatowicz, Ewa Gorodkiewicz

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Beata SzymanskaFaculty of Chemistry, Bioanalysis Laboratory, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland.
Zenon LukaszewskiFaculty of Chemical Technology, Poznan University of Technology, Pl. Sklodowskiej-Curie 5, 60-965 Poznan, Poland.ORCID 0000-0003-1968-1072
Kinga Hermanowicz-SzamatowiczDepartment of Clinical Oncology, Comprehensive Cancer Center, Ogrodowa 12, 15-027 Bialystok, Poland.ORCID 0000-0002-8260-2376
Ewa GorodkiewiczFaculty of Chemistry, Bioanalysis Laboratory, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland.
University of Białystok · PLGreater Poland Cancer Center · PLPoznań University of Technology · PL

Funding

Polish Ministry of Education and Science BST-162
6 · The paper itself

Abstract

Diagnostics based on the determination of biomarkers in body fluids will be more successful when several biomarkers are determined. A multiple-array SPRi biosensor for the simultaneous determination of CA125, HE4, CEA, IL-6 and aromatase has been developed. Five individual biosensors were placed on the same chip. Each of them consisted of a suitable antibody covalently immobilized onto a gold chip surface via a cysteamine linker by means of the NHS/EDC protocol. The biosensor for IL-6 works in the pg mL

Indexed as

AromataseBiosensing TechniquesBiomarkers, TumorFemaleHumansInterleukin-6WAP Four-Disulfide Core Domain Protein 2AromataseBiomarkers, TumorInterleukin-6WAP Four-Disulfide Core Domain Protein 2aromataseCA125CEAendometriosisHE4IL-6ovarian cancer

Identifiers

PMID36832045
PMCPMC9954693
OpenAlexW4321106577

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.