Evidence map›Paper›PMID 36832041›Full record

ArticleBiosensors2023

Validation of Rapid and Economic Colorimetric Nanoparticle Assay for SARS-CoV-2 RNA Detection in Saliva and Nasopharyngeal Swabs.

María Armesto, Mathias Charconnet, José M Marimón, Cristina Lía Fernández Regueiro, Jia Jia, Tingdong Yan, Ane Sorarrain, Marek Grzelczak, María Sanromán, Mónica Vicente and 6 more

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

María ArmestoMolecular Oncology Group, Biodonostia Research Institute, 20014 San Sebastián, Spain.
Mathias CharconnetSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.ORCID 0000-0003-2786-8750
José M MarimónRespiratory Infection and Antimicrobial Resistance Group, Biodonostia Research Institute, 20014 San Sebastián, Spain.ORCID 0000-0002-2787-7094
Cristina Lía Fernández RegueiroSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.ORCID 0000-0001-6709-2550
Jia JiaSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.ORCID 0000-0001-7967-4275
Tingdong YanSchool of Life Sciences, Shanghai University, Shanghai 201907, China.
Ane SorarrainRespiratory Infection and Antimicrobial Resistance Group, Biodonostia Research Institute, 20014 San Sebastián, Spain.
Marek GrzelczakColloidal Systems Chemistry, Centro de Física de Materiales (CSIC-UPV/EHU), 20018 San Sebastián, Spain.ORCID 0000-0002-3458-8450
María SanrománColloidal Systems Chemistry, Centro de Física de Materiales (CSIC-UPV/EHU), 20018 San Sebastián, Spain.
Mónica VicenteMolecular Oncology Group, Biodonostia Research Institute, 20014 San Sebastián, Spain.ORCID 0000-0001-5041-1674
Boris KlempaBiomedical Research Center, Institute of Virology, Slovak Academy of Sciences, Dúbravská Cesta 9, Bratislava 845 05, Slovakia.ORCID 0000-0002-6931-1224
Javier ZubiriaSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.
Yuan PengSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.
Lei ZhangSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.
Jianhua ZhangSino-Swiss Institute of Advanced Technology (SSIAT), Shanghai University, Shanghai 201907, China.
Charles H LawrieMolecular Oncology Group, Biodonostia Research Institute, 20014 San Sebastián, Spain.ORCID 0000-0002-8882-1131
Shanghai University · CNBiogipuzkoa Health Research Institute · ESMaterial Physics Center · ESBiomedical Research Center of the Slovak Academy of Sciences · SKIkerbasque · ES

Funding

EITB Maratoia BIO21/COV/032/BDIniciativa Medtech BIO21/COV/032/BD
6 · The paper itself

Abstract

Even with the widespread uptake of vaccines, the SARS-CoV-2-induced COVID-19 pandemic continues to overwhelm many healthcare systems worldwide. Consequently, massive scale molecular diagnostic testing remains a key strategy to control the ongoing pandemic, and the need for instrument-free, economic and easy-to-use molecular diagnostic alternatives to PCR remains a goal of many healthcare providers, including WHO. We developed a test (Repvit) based on gold nanoparticles that can detect SARS-CoV-2 RNA directly from nasopharyngeal swab or saliva samples with a limit of detection (LOD) of 2.1 × 10

Indexed as

COVID-19Metal NanoparticlesColorimetryGoldHumansNasopharynxPandemicsRNA, ViralSalivaSARS-CoV-2Specimen HandlingGoldRNA, ViralcolorimetricnanoparticlePOC diagnosticSARS-CoV-2

Identifiers

PMID36832041
PMCPMC9954569
OpenAlexW4320918046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.