ArticleBiosensors2023
Highly Sensitive Detection of Chymotrypsin Based on Metal Organic Frameworks with Peptides Sensors.
Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 6 citations in OpenAlex.
- Highly Sensitive Detection of Chymotrypsin Using Gold Nanoclusters with Peptide Sensors.Micromachines · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, peptides and composite nanomaterials based on copper nanoclusters (CuNCs) were used to detect chymotrypsin. The peptide was a chymotrypsin-specific cleavage peptide. The amino end of the peptide was covalently bound to CuNCs. The sulfhydryl group at the other end of the peptide can covalently combine with the composite nanomaterials. The fluorescence was quenched by fluorescence resonance energy transfer. The specific site of the peptide was cleaved by chymotrypsin. Therefore, the CuNCs were far away from the surface of the composite nanomaterials, and the intensity of fluorescence was restored. The limit of detection (LOD) using Porous Coordination Network (PCN)@graphene oxide (GO) @ gold nanoparticle (AuNP) sensor was lower than that of using PCN@AuNPs. The LOD based on PCN@GO@AuNPs was reduced from 9.57 pg mL
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.