Evidence map›Paper›PMID 36832013›Full record

ArticleBiosensors2023

Electrochemical Impedance Immunoassay for ALS-Associated Neurofilament Protein: Matrix Effect on the Immunoplatform.

Omair Adil, Mohtashim H Shamsi

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Omair AdilSchool of Chemical and Biomolecular Sciences, Southern Illinois University, 1245 Lincoln Drive, Carbondale, IL 62918, USA.
Mohtashim H ShamsiSchool of Chemical and Biomolecular Sciences, Southern Illinois University, 1245 Lincoln Drive, Carbondale, IL 62918, USA.ORCID 0000-0002-5463-811X
Southern Illinois University Carbondale · US

Funding

Neurodegenerative Research Inc. N/A
6 · The paper itself

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder, which has complex diagnostic steps. Electrochemical immunoassays may make the diagnosis simpler and faster. Here, we present the detection of ALS-associated neurofilament light chain (Nf-L) protein through an electrochemical impedance immunoassay on reduced graphene oxide (rGO) screen-printed electrodes. The immunoassay was developed in two different media, i.e., buffer and human serum, to compare the effect of the media on their figures of merit and calibration models. The label-free charge transfer resistance (R

Indexed as

Amyotrophic Lateral SclerosisNeurofilament ProteinsElectric ImpedanceElectrodesFemaleHumansImmunoassayMaleProteinsNeurofilament ProteinsProteinsamyotrophic lateral sclerosisdiagnosticselectrochemical impedance spectroscopyimmunoassayneurofilament-light

Identifiers

PMID36832013
PMCPMC9954657
OpenAlexW4319753806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.