Evidence map›Paper›PMID 36832008›Full record

ArticleBiosensors2023

Quantum Dot-Sensitised Estrogen Receptor-α-Based Biosensor for 17β-Estradiol.

Abongile N Jijana, Usisipho Feleni, Peter M Ndangili, Mawethu Bilibana, Rachel F Ajayi, Emmanuel I Iwuoha

Abstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abongile N JijanaNanotechnology Innovation Centre, Advanced Materials Division, Mintek, Private Bag X3015, Randburg, Johannesburg 2125, South Africa.ORCID 0000-0002-4425-9386
Usisipho FeleniInstitute for Nanotechnology and Water Sustainability (iNanoWS), College of Science, Engineering and Technology, University of South Africa, Florida Campus, P/Bag X6, Florida, Roodepoort, Johannesburg 1710, South Africa.
Peter M NdangiliSchool of Chemistry and Material Science, The Technical University of Kenya, Nairobi P.O. Box 52428-00200, Kenya.
Mawethu BilibanaDepartment of Chemistry, School of Physical and Chemical Sciences, Faculty of Natural and Agricultural Sciences, North-West University (Mafikeng Campus), Private Bag X2046, Mmabatho 2735, South Africa.ORCID 0000-0002-2638-874X
Rachel F AjayiSensorLab (University of the Western Cape Sensor Laboratories), 4th Floor Chemical Sciences Building, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa.ORCID 0000-0003-0899-433X
Emmanuel I IwuohaSensorLab (University of the Western Cape Sensor Laboratories), 4th Floor Chemical Sciences Building, University of the Western Cape, Private Bag X17, Bellville, Cape Town 7535, South Africa.ORCID 0000-0001-6102-0433

Funding

DSI/Nanotechnology Innovation Centre-Mintek and National Research Foundation (NRF)-South African Research Chair Initiative (SARChI) 85102
6 · The paper itself

Abstract

17β-estradiol (E2) is an important natural female hormone that is also classified as an estrogenic endocrine-disrupting compound (e-EDC). It is, however, known to cause more damaging health effects compared to other e-EDCs. Environmental water systems are commonly contaminated with E2 that originates from domestic effluents. The determination of the level of E2 is thus very crucial in both wastewater treatment and in the aspect of environmental pollution management. In this work, an inherent and strong affinity of the estrogen receptor-α (ER-α) for E2 was used as a basis for the development of a biosensor that was highly selective towards E2 determination. A gold disk electrode (AuE) was functionalised with a 3-mercaptopropionic acid-capped tin selenide (SnSe-3MPA) quantum dot to produce a SnSe-3MPA/AuE electroactive sensor platform. The ER-α-based biosensor (ER-α/SnSe-3MPA/AuE) for E2 was produced by the amide chemistry of carboxyl functional groups of SnSe-3MPA quantum dots and the primary amines of ER-α. The ER-α/SnSe-3MPA/AuE receptor-based biosensor exhibited a formal potential (E

Indexed as

Biosensing TechniquesEndocrine DisruptorsQuantum DotsEstradiolFemaleHumansReceptors, EstrogenEndocrine DisruptorsEstradiolReceptors, Estrogen17β-estradiol (E2)endocrine-disrupting compounds (EDC)estrogen receptor-alpha (ER-α)hormonenanomaterialsquantum dotsSnSe

Identifiers

PMID36832008
PMCPMC9954354

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.