Evidence map›Paper›PMID 36831956›Full record

ArticleBiosensors2023

Flexible Label-Free Platinum and Bio-PET-Based Immunosensor for the Detection of SARS-CoV-2.

Rodrigo Vieira Blasques, Paulo Roberto de Oliveira, Cristiane Kalinke, Laís Canniatti Brazaca, Robert D Crapnell, Juliano Alves Bonacin, Craig E Banks, Bruno Campos Janegitz

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Rodrigo Vieira BlasquesLaboratory of Sensors, Nanomedicine and Nanostructured Materials, Federal University of São Carlos, Araras 13600-970, Brazil.ORCID 0000-0001-7059-3145
Paulo Roberto de OliveiraLaboratory of Sensors, Nanomedicine and Nanostructured Materials, Federal University of São Carlos, Araras 13600-970, Brazil.
Cristiane KalinkeFaculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.ORCID 0000-0002-9718-0292
Laís Canniatti BrazacaDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-0456-7552
Robert D CrapnellFaculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.ORCID 0000-0002-8701-3933
Juliano Alves BonacinInstitute of Chemistry, University of Campinas, Campinas 13083-970, Brazil.
Craig E BanksFaculty of Science and Engineering, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, UK.ORCID 0000-0002-0756-9764
Bruno Campos JanegitzLaboratory of Sensors, Nanomedicine and Nanostructured Materials, Federal University of São Carlos, Araras 13600-970, Brazil.ORCID 0000-0001-9707-9795
Manchester Metropolitan University · GBUniversidade Federal de São Carlos · BRHarvard University · USUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001; 88887.712315/2022-00; 88887.636021/2021-00; 88887.510880/2020-00National Council for Scientific and Technological Development 303338/2019-9; 120557/2019-3; 308203/2021-6São Paulo Research Foundation 2022/01601-7; 2021/07989-4; 2019/23177-0; 2019/00473-2; 2018/19750-3; 2017/21097-3; 2013/22127-2
6 · The paper itself

Abstract

The demand for new devices that enable the detection of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) at a relatively low cost and that are fast and feasible to be used as point-of-care is required overtime on a large scale. In this sense, the use of sustainable materials, for example, the bio-based poly (ethylene terephthalate) (Bio-PET) can be an alternative to current standard diagnostics. In this work, we present a flexible disposable printed electrode based on a platinum thin film on Bio-PET as a substrate for the development of a sensor and immunosensor for the monitoring of COVID-19 biomarkers, by the detection of L-cysteine and the SARS-CoV-2 spike protein, respectively. The electrode was applied in conjunction with 3D printing technology to generate a portable and easy-to-analyze device with a low sample volume. For the L-cysteine determination, chronoamperometry was used, which achieved two linear dynamic ranges (LDR) of 3.98-39.0 μmol L

Indexed as

Biosensing TechniquesCOVID-19CysteineElectrochemical TechniquesHumansImmunoassayPlatinumSARS-CoV-2Spike Glycoprotein, CoronavirusCysteinePlatinumSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-23D printing technologyBio-PETflexible electrodeplatinum-based electrodepoint-of-careSARS-CoV-2 diagnostics

Identifiers

PMID36831956
PMCPMC9954080
OpenAlexW4318207593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.