Evidence map›Paper›PMID 36831930›Full record

ReviewBiosensors2023

Microfluidics for COVID-19: From Current Work to Future Perspective.

Qi Li, Xingchen Zhou, Qian Wang, Wenfang Liu, Chuanpin Chen

Abstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi LiDepartment of Pharmacy, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410017, China.
Xingchen ZhouDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha 410017, China.
Qian WangDepartment of Pharmacy, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410017, China.
Wenfang LiuDepartment of Pharmacy, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410017, China.
Chuanpin ChenDepartment of Pharmacy, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410017, China.

Funding

Independent Exploration and Innovation 830 Program for Graduate Students of Central South University 2022zzts898National Natural Science Foundation of China 81202378National Natural Science Foundation of China 81311140268Project of Hunan Science and Technology 2020JJ9011Project of Hunan Science and Technology 2020JJ9020Project of Hunan Science and Technology 2021JJ80078
6 · The paper itself

Abstract

Spread of coronavirus disease 2019 (COVID-19) has significantly impacted the public health and economic sectors. It is urgently necessary to develop rapid, convenient, and cost-effective point-of-care testing (POCT) technologies for the early diagnosis and control of the plague's transmission. Developing POCT methods and related devices is critical for achieving point-of-care diagnosis. With the advantages of miniaturization, high throughput, small sample requirements, and low actual consumption, microfluidics is an essential technology for the development of POCT devices. In this review, according to the different driving forces of the fluid, we introduce the common POCT devices based on microfluidic technology on the market, including paper-based microfluidic, centrifugal microfluidic, optical fluid, and digital microfluidic platforms. Furthermore, various microfluidic-based assays for diagnosing COVID-19 are summarized, including immunoassays, such as ELISA, and molecular assays, such as PCR. Finally, the challenges of and future perspectives on microfluidic device design and development are presented. The ultimate goals of this paper are to provide new insights and directions for the development of microfluidic diagnostics while expecting to contribute to the control of COVID-19.

Indexed as

COVID-19Microfluidic Analytical TechniquesHumansImmunoassayLab-On-A-Chip DevicesMicrofluidicsPoint-of-Care SystemsPoint-of-Care TestingCOVID-19immunoassaysmicrofluidicmolecular assays

Identifiers

PMID36831930
PMCPMC9953302

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.