Evidence map›Paper›PMID 36831911›Full record

ReviewBrain sciences2023

A Systematic Review on the Potential of Aspirin to Reduce Cardiovascular Risk in Schizophrenia.

Joseph Dao, Savreen Saran, Melody Wang, Christina Michael, Nhu-Y Phan, Alfredo Bellon

Open access · goldAbstract readReview
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joseph DaoCollege of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.ORCID 0000-0002-6553-4375
Savreen SaranCollege of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.ORCID 0000-0003-2418-1582
Melody WangCollege of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.
Christina MichaelCollege of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.
Nhu-Y PhanCollege of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.
Alfredo BellonDepartment of Psychiatry and Behavioral Health, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA.ORCID 0000-0003-2669-084X
Pennsylvania State University · USPenn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD), including heart disease and stroke, continues to be the leading cause of death worldwide. Patients with mental health disorders, including schizophrenia (SCZ) are known to have an increased risk for CVD. Given the association with metabolic syndrome, patients with SCZ are often prescribed metformin and statins but its impact remains unsatisfactory. The use of aspirin (ASA) to decrease cardiovascular risk in the general population has been thoroughly investigated and clear guidelines are currently in place. Since adjuvant treatment with ASA could possibly decrease CVD risk and mortality in SCZ, we conducted a systematic review of the literature to determine the state of the current literature on this subject. Our systematic review points to gaps in the literature on CVD prevention in SCZ and illustrates an obvious need for further research. Although several studies have shown increased CVD risk in SCZ, to date, no research has been conducted on the utilization of CVD preventative treatment such as ASA for SCZ.

Indexed as

anti-inflammatoryaspirincardiovascularmental-healthmetabolicschizophrenia

Identifiers

PMID36831911
PMCPMC9954190
OpenAlexW4321457627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.