Evidence map›Paper›PMID 36831863›Full record

ReviewBrain sciences2023

Impact of Physical Exercise Alone or in Combination with Cognitive Remediation on Cognitive Functions in People with Schizophrenia: A Qualitative Critical Review.

Giacomo Deste, Daniele Corbo, Gabriele Nibbio, Mauro Italia, Dario Dell'Ovo, Irene Calzavara-Pinton, Jacopo Lisoni, Stefano Barlati, Roberto Gasparotti, Antonio Vita

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Are cognitive deficits more severe among people with treatment-resistant schizophrenia than treatment responders?Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giacomo DesteDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Daniele CorboDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0001-5078-6636
Gabriele NibbioDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Mauro ItaliaDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Dario Dell'OvoDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Irene Calzavara-PintonDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Jacopo LisoniDepartment of Mental Health and Addiction Services, ASST Spedali Civili of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-4091-6502
Stefano BarlatiDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-1784-3915
Roberto GasparottiDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.
Antonio VitaDepartment of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise and cognitive remediation represent the psychosocial interventions with the largest basis of evidence attesting their effectiveness in improving cognitive performance in people living with schizophrenia according to recent international guidance. The aims of this review are to provide an overview of the literature on physical exercise as a treatment for cognitive impairment in schizophrenia and of the studies that have combined physical exercise and cognitive remediation as an integrated rehabilitation intervention. Nine meta-analyses and systematic reviews on physical exercise alone and seven studies on interventions combining physical exercise and cognitive remediation are discussed. The efficacy of physical exercise in improving cognitive performance in people living with schizophrenia is well documented, but more research focused on identifying moderators of participants response and optimal modalities of delivery is required. Studies investigating the effectiveness of integrated interventions report that combining physical exercise and cognitive remediation provides superior benefits and quicker improvements compared to cognitive remediation alone, but most studies included small samples and did not explore long-term effects. While physical exercise and its combination with cognitive remediation appear to represent effective treatments for cognitive impairment in people living with schizophrenia, more evidence is currently needed to better understand how to implement these treatments in psychiatric rehabilitation practice.

Indexed as

cognitive functioningcognitive remediationintegrated interventionsphysical exercisepsychiatric rehabilitationpsychosocial interventionsrecoveryschizophrenia

Identifiers

PMID36831863
PMCPMC9954055
OpenAlexW4320728715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.