Evidence map›Paper›PMID 36831688›Full record

ArticleCancers2023

Variation in Post-Transplant Cancer Incidence among Italian Kidney Transplant Recipients over a 25-Year Period.

Pierluca Piselli, Diego Serraino, Claudia Cimaglia, Lucrezia Furian, Luigi Biancone, Ghil Busnach, Nicola Bossini, Paola Todeschini, Maurizio Iaria, Franco Citterio and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Post-Kidney Transplant Cancer: A Real-World Retrospective Analysis From a Single Italian Center.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  8. Adverse Drug Events after Kidney Transplantation.Journal of personalized medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 17 institutions in 1 country.

Pierluca PiselliDepartment of Epidemiology and Pre-Clinical Research, National Institute for Infectious Diseases "L. Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0002-7342-0263
Diego SerrainoUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy.ORCID 0000-0003-0565-8920
Claudia CimagliaDepartment of Epidemiology and Pre-Clinical Research, National Institute for Infectious Diseases "L. Spallanzani" IRCCS, 00149 Rome, Italy.
Lucrezia FurianUnit of Kidney and Pancreas Transplantation, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, 35128 Padova, Italy.
Luigi BianconeDivision of Nephrology Dialysis and Transplantation, Renal Transplantation Center "A. Vercellone", Città della Salute e della Scienza University Hospital, 10126 Turin, Italy.
Ghil BusnachGrande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0002-4013-050X
Nicola BossiniUnit of Nephrology, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Paola TodeschiniDepartment of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, IRCCS S. Orsola Hospital, University of Bologna, 40138 Bologna, Italy.
Maurizio IariaDepartment of General and Specialized Surgery, Division of General Surgery, Transplant Surgery Unit, Parma University Hospital, 43126 Parma, Italy.
Franco CitterioDepartment of Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-0489-6337
Mariarosaria CampiseUnit of Nephrology, Dialysis, and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy.
Massimiliano VerouxOrgan Transplantation Unit, Department of Medical and Surgical Sciences and Advanced Technologies, University Hospital of Catania, 95123 Catania, Italy.ORCID 0000-0002-2780-6421
Giuseppe TisoneUOC Transplant Unit, Department of Surgery, Tor Vergata University, 00133 Rome, Italy.
Vincenzo CantaluppiNephrology and Kidney Transplantation Unit, Department of Translational Medicine, University of Piemonte Orientale (UPO), "Maggiore della Carità" University Hospital, 28100 Novara, Italy.ORCID 0000-0002-4120-3555
Margherita ManginoNephrology, Dialysis, Transplantation Unit, Ca' Foncello Hospital, 31100 Treviso, Italy.
Simona SimoneNephrology, Dialysis and Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy.
Davide ArgiolasRenal Transplant Unit, Azienda Ospedaliera Brotzu, 09047 Cagliari, Italy.
Andrea AmbrosiniRenal Transplant Unit, Azienda Ospedaliera Ospedale di Circolo e Fondazione Macchi, 21100 Varese, Italy.
Francesco PisaniGeneral and Transplant Surgery Department, University of L'Aquila, 67100 L'Aquila, Italy.
Flavia CaputoNephrology Dialysis and Renal Transplant Department, Civico and Di Cristina Hospital, 90127 Palermo, Italy.
Martina TaborelliUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy.ORCID 0000-0002-6731-7569
Italian Transplant and Cancer Cohort Study
Centro di Riferimento Oncologico · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITAgostino Gemelli University Polyclinic · ITAzienda Ospedaliera G. Brotzu · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCa' Foncello Hospital · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale di Circolo e Fondazione Macchi · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Bari Aldo Moro · ITUniversity of Bologna · ITUniversity of Catania · ITUniversity of L'Aquila · ITUniversity of Padua · ITUniversity of Parma · ITUniversity of Rome Tor Vergata · IT

Funding

CRO Aviano "5x1000 (Redditi 2018)" - Seed Grant to MTItalian Association for Research on Cancer (AIRC IG No. 19112)Italian Ministry of Health (Ricerca Corrente to IRCCS INMI L. Spallanzani, and Ricerca Corrente to IRCCS CRO Aviano)
6 · The paper itself

Abstract

This cohort study examined 25-year variations in cancer incidence among 11,418 Italian recipients of kidney transplantation (KT) from 17 Italian centers. Cancer incidence was examined over three periods (1997-2004; 2005-2012; and 2013-2021) by internal (Incidence rate ratio-IRR) and external (standardized incidence ratios-SIR) comparisons. Poisson regression was used to assess trends. Overall, 1646 post-transplant cancers were diagnosed, with incidence rates/1000 person-years ranging from 15.5 in 1997-2004 to 21.0 in 2013-2021. Adjusted IRRs showed a significant reduction in incidence rates across periods for all cancers combined after exclusion of nonmelanoma skin cancers (IRR = 0.90, 95% confidence interval-CI: 0.76-1.07 in 2005-2012; IRR = 0.72, 95% CI: 0.60-0.87 in 2013-2021 vs. 1997-2004; P

Indexed as

cohort studyimmunosuppressionItalykidney transplanttrendvirus-related malignancy

Identifiers

PMID36831688
PMCPMC9954633
OpenAlexW4321442621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.