Evidence map›Paper›PMID 36831667›Full record

ArticleCancers2023

Prognostic Factors in Pseudomyxoma Peritonei with Emphasis on the Predictive Role of Peritoneal Cancer Index and Tumor Markers.

Sebastian Blaj, David Dora, Zoltan Lohinai, Zoltan Herold, Attila Marcell Szasz, Jonas Herzberg, Roland Kodacsi, Saher Baransi, Hans Jürgen Schlitt, Matthias Hornung and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Peritoneal metastasis histological grade independently predicts outcome in pseudomyxoma peritonei treated with curative surgery.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Sebastian BlajDepartment of General and Visceral Surgery, Hospital Barmherzige Brüder, D-93049 Regensburg, Germany.ORCID 0000-0001-5830-9797
David DoraDepartment of Anatomy, Histology and Embryology, Semmelweis University, H-1094 Budapest, Hungary.
Zoltan LohinaiTranslational Medicine Institute, Semmelweis University, H-1094 Budapest, Hungary.
Zoltan HeroldDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.ORCID 0000-0001-5990-4889
Attila Marcell SzaszDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, H-1083 Budapest, Hungary.
Jonas HerzbergDepartment of Surgery, Krankenhaus Reinbek St. Adolf-Stift, D-21465 Reinbek, Germany.ORCID 0000-0003-3562-6575
Roland KodacsiDepartment of Cardiothoracic Surgery, University Medical Center, D-93053 Regensburg, Germany.
Saher BaransiDepartment of Gynecology and Obstetrics, Florence Nightingale Hospital, D-40489 Düsseldorf, Germany.
Hans Jürgen SchlittDepartment of Surgery, University Hospital, 93053 Regensburg, Germany.ORCID 0000-0002-3874-0296
Matthias HornungDepartment of Surgery, University Hospital, 93053 Regensburg, Germany.
Jens M WernerDepartment of Surgery, University Hospital, 93053 Regensburg, Germany.ORCID 0000-0001-7156-4370
Przemyslaw SlowikDepartment of Surgery, University Hospital, 93053 Regensburg, Germany.
Miklos AcsDepartment of General and Visceral Surgery, Hospital Barmherzige Brüder, D-93049 Regensburg, Germany.
Pompiliu PisoDepartment of General and Visceral Surgery, Hospital Barmherzige Brüder, D-93049 Regensburg, Germany.
University Hospital Regensburg · DESemmelweis University · HUKrankenhaus Barmherzige Brüder · DEKrankenhaus Reinbek - Startseite · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPseudomyxoma peritonei (PMP) is a rare peritoneal condition where mucus-secreting tumorous cells progressively produce a thick, gelatin-like substance. The prognosis of patients with PMP is determined by the degree of cellularity within the mucin (low-grade (LAMN) vs. high-grade (HAMN) histologic features) and by the extent of the disease.

methodsPrognostic relevance of tumor markers CA19-9 and CEA, gender, Peritoneal Cancer Index (PCI), and completeness of cytoreduction (CC) after cytoreductive surgery were evaluated on 193 consecutive PMP patients, based on a retrospective analysis of prospectively gathered data from a German tertial referral center.

resultsWe demonstrated that low PCI, CC0 status, low-grade histology, and female gender were independent positive prognostic factors for both overall survival (OS) and progression-free survival (PFS). Furthermore, LAMN patients with achieved CC0 status show significantly better OS and PFS compared to those with CC1 status (

conclusionOur study confirmed the prognostic role of tumor markers and emphasized the importance of CC status and PCI in a large cohort of PMP- and LAMN patients.

Indexed as

biomarkersca-19-9 antigencarcinoembryonic antigencytoreductive surgeryhyperthermic intraperitoneal chemotherapylow-grade appendiceal mucinous neoplasmsperitoneal cancer indexpseudomyxoma peritoneitumor

Identifiers

PMID36831667
PMCPMC9954733
OpenAlexW4321377199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.