ReviewCancers2023
Histopathological Aspects of the Prognostic Factors for Salivary Gland Cancers.
Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Classification of Salivary Gland Tumors on Ultrasound Using Artificial Intelligence: A Systematic Review and Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Pooled it
- Expression of Prostate-Specific Membrane Antigen in Salivary Gland Tumors.Oncology and therapy · 2026Article
- Clinicopathologic Features and Postoperative Outcomes of Parotidectomy: A 16-Year Retrospective Cohort Study from a Tertiary Referral Center.Diagnostics (Basel, Switzerland) · 2026Article
- Risk-adapted neck dissection in salivary gland carcinoma: integrating occult nodal metastasis patterns with contemporary guidelines.Frontiers in oncology · 2026Review
- Expression of phosphohistone H3 and X-linked inhibitors of apoptosis-related proteins in mucoepidermoid carcinoma and adenoid cystic carcinoma of salivary glands.Scientific reports · 2025Article
- [Clinical and molecular epidemiology of malignant salivary gland tumors].Laryngo- rhino- otologie · 2025Review
- Core Needle Biopsy May Predict Prognosis Preoperatively in Parotid Cancer.Clinical and experimental otorhinolaryngology · 2025Article
- Adenoid cystic carcinoma of the external auditory canal with metastasis to the cerebellopontine angle mimicking vestibular schwannoma: a case report and literature review.Frontiers in oncology · 2025Article
- Clinical and Morphological Aspects of Aggressive Salivary Gland Mixed Tumors: A Narrative Review.Diagnostics (Basel, Switzerland) · 2024Review
- Current Developments in Diagnosis of Salivary Gland Tumors: From Structure to Artificial Intelligence.Life (Basel, Switzerland) · 2024Review
- Review
- Machine learning-based survival prediction nomogram for postoperative parotid mucoepidermoid carcinoma.Scientific reports · 2024Article
- Tumor budding - a potential biomarker in low grade salivary gland carcinomas?Frontiers in oncology · 2024Article
- Prognostic Significance of Histopathological Parameters for Salivary Gland Adenoid Cystic Carcinoma.Dentistry journal · 2023Review
- Role of Histone Deacetylases in the Pathogenesis of Salivary Gland Tumors and Therapeutic Targeting Options.International journal of molecular sciences · 2023Review
- Metastatic Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Sublingual Salivary Gland.Cureus · 2023Article
- The Epigenesis of Salivary Glands Carcinoma: From Field Cancerization to Carcinogenesis.Cancers · 2023Review
- Impact of Amplified Oncogenes on Salivary Gland Carcinomas.Cancer diagnosis & prognosisReview
- Mutational Signatures in Salivary Gland Carcinomas.Cancer diagnosis & prognosisReview
- PTEN Deregulation Mechanisms in Salivary Gland Carcinomas.Cancer diagnosis & prognosisReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salivary gland cancers (SGCs) are diagnosed using histopathological examination, which significantly contributes to their progression, including lymph node/distant metastasis or local recurrence. In the current World Health Organization (WHO) Classification of Head and Neck Tumors: Salivary Glands (5th edition), malignant and benign epithelial tumors are classified into 21 and 15 tumor types, respectively. All malignant tumors have the potential for lymph node/distant metastasis or local recurrence. In particular, mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (AdCC), salivary duct carcinoma, salivary carcinoma, not otherwise specified (NOS, formerly known as adenocarcinoma, NOS), myoepithelial carcinoma, epithelial-myoepithelial carcinoma, and carcinoma ex pleomorphic adenoma (PA) are relatively prevalent. High-grade transformation is an important aspect of tumor progression in SGCs. MEC, AdCC, salivary carcinoma, and NOS have a distinct grading system; however, a universal histological grading system for SGCs has not yet been recommended. Conversely, PA is considered benign; nonetheless, it should be cautiously treated to avoid the development of metastasizing/recurrent PA. The aim of this review is to describe the current histopathological aspects of the prognostic factors for SGCs and discuss the genes or molecules used as diagnostic tools that might have treatment target potential in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.