Evidence map›Paper›PMID 36831574›Full record

ArticleCancers2023

Electronic Patient Reported Outcome (ePRO) Measures in Patients with Soft Tissue Sarcoma (STS) Receiving Palliative Treatment.

Silvia Hofer, Leopold Hentschel, Stephan Richter, Veronika Blum, Michael Kramer, Bernd Kasper, Christoph Riese, Markus K Schuler

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness of ePRO-based symptom management for cancer patients: a systematic review and meta-analysis of randomized controlled studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia HoferDepartment of Neurology, University Hospital Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-0831-2098
Leopold HentschelDivision of Psycho-Oncology, NCT/UCC, University Hospital Carl Gustav Carus, Technical University of Dresden, 01307 Dresden, Germany.
Stephan RichterClinic and Polyclinic for Internal Medicine I, Sarcoma Center, NCT/UCC, University Hospital Carl Gustav Carus, Technical University of Dresden, 01307 Dresden, Germany.
Veronika BlumDepartment of Internal Medicine, Cantonal Hospital Lucerne, 6002 Lucerne, Switzerland.
Michael KramerAvenCell Europe GmbH Dresden, 01307 Dresden, Germany.
Bernd KasperSarcoma Unit, Mannheim Cancer Center (MCC), Mannheim University Medical Center, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0001-8425-8356
Christoph RieseDTB Gesellschaft für digitale Therapiebegleitung mbH, 07745 Jena, Germany.
Markus K SchulerClinic and Polyclinic for Internal Medicine I, Sarcoma Center, NCT/UCC, University Hospital Carl Gustav Carus, Technical University of Dresden, 01307 Dresden, Germany.ORCID 0000-0003-0764-1049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PazoQoL prospective, randomized, controlled, multicenter study was designed to continuously assess global health related quality of life (HRQoL) during treatment with pazopanib or physician-preferred chemotherapy over a 9-week period. The questionnaires were completed by the patients at home with great reliability during this time period. Continuous electronic patient reported outcome (ePRO) enabled early detection of the onset of deterioration and timely initiation of countermeasures. The Cancer Therapy Satisfaction Questionnaire (CTSQ) showed high interindividual variability and decline over a 9-week period, whereas the Time Trade-off (TTO) proved to be an efficient method for assessing individual benefit from cancer therapy. In our cohort, the TTO clearly demonstrated that the prolongation of life and the side effect profile of continued therapy were not as satisfactory as expected by patients when starting a new therapy. Although the study had to be stopped early due to the pandemic, our findings could translate into clinical practice without much effort and outside of a trial.

Indexed as

electronic patient reported outcomehealth related quality of lifepalliative treatmentrandomized controlled trialsoft tissue sarcoma

Identifiers

PMID36831574
PMCPMC9954494

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.