Evidence map›Paper›PMID 36831529›Full record

ArticleCancers2023

A Simple, Test-Based Method to Control the Overestimation Bias in the Analysis of Potential Prognostic Tumour Markers.

Marzia Ognibene, Annalisa Pezzolo, Roberto Cavanna, Davide Cangelosi, Stefania Sorrentino, Stefano Parodi

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marzia OgnibeneU.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0003-3698-9319
Annalisa PezzoloIRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0001-6321-5701
Roberto CavannaUnità di Bioinformatica Clinica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0003-4070-6342
Davide CangelosiUnità di Bioinformatica Clinica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-6010-5619
Stefania SorrentinoU.O.C. Oncologia Pediatrica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0001-7381-0133
Stefano ParodiDirezione Scientifica, IRCCS Istituto Giannina Gaslini, 16147 Genova, Italy.ORCID 0000-0002-9193-1622

Funding

Compagnia di San Paolo ID ROL 20207Ministero della Salute MSALRC22
6 · The paper itself

Abstract

The early evaluation of prognostic tumour markers is commonly performed by comparing the survival of two groups of patients identified on the basis of a cut-off value. The corresponding hazard ratio (

Indexed as

Cox modelE2F1hazard rationeuroblastomaoverestimation biassurvival analysistumour markers

Identifiers

PMID36831529
PMCPMC9953998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.