Evidence map›Paper›PMID 36831497›Full record

ArticleCancers2023

Determinants of Pre-Surgical Treatment in Primary Rectal Cancer: A Population-Based Study.

Israa Imam, Klara Hammarström, Bengt Glimelius

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Israa ImamDepartment of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0002-0232-2391
Klara HammarströmDepartment of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0002-8271-2241
Bengt GlimeliusDepartment of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0002-5440-791X
Uppsala University · SE

Funding

Swedish Cancer Society 190382PJ01H
6 · The paper itself

Abstract

When preoperative radiotherapy (RT) is best used in rectal cancer is subject to discussions and guidelines differ. To understand the selection mechanisms, we analysed treatment decisions in all patients diagnosed between 2010-2020 in two Swedish regions (Uppsala with a RT department and Dalarna without). Information on staging and treatment (direct surgery, short-course RT, or combinations of RT/chemotherapy) in the Swedish Colorectal Cancer Registry were used. Staging magnetic resonance imaging (MRI) permitted a division into risk groups, according to national guidelines. Logistic regression explored associations between baseline characteristics and treatment, while Cohen's kappa tested congruence between clinical and pathologic stages. A total of 1150 patients without synchronous metastases were analysed. Patients from Dalarna were older, had less advanced tumours and were pre-treated less often (52% vs. 63%,

Indexed as

chemoradiotherapymagnetic resonance imagingneoadjuvant therapypopulation-basedpreoperative therapyradiotherapyrectal cancertreatment guidelines

Identifiers

PMID36831497
PMCPMC9954598
OpenAlexW4320494345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.