Evidence map›Paper›PMID 36831471›Full record

ArticleCancers2023

Surveillance Value of Apparent Diffusion Coefficient Maps: Multiparametric MRI in Active Surveillance of Prostate Cancer.

Aleksandar Georgiev, Lyubomir Chervenkov, Mladen Doykov, Katya Doykova, Petar Uchikov, Silvia Tsvetkova

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aleksandar GeorgievDepartment of Diagnostic Imaging, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.
Lyubomir ChervenkovDepartment of Diagnostic Imaging, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.ORCID 0000-0002-8380-5992
Mladen DoykovDepartment of Urology and General Medicine, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.ORCID 0000-0002-7029-8397
Katya DoykovaDepartment of Diagnostic Imaging, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.ORCID 0000-0001-6433-7970
Petar UchikovDepartment of Special Surgery, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.
Silvia TsvetkovaDepartment of Diagnostic Imaging, Medical Faculty, Medical University Plovdiv, Bul. Vasil Aprilov 15A, 4002 Plovdiv, Bulgaria.ORCID 0000-0002-0757-0140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to establish the value of apparent diffusion coefficient maps and other magnetic resonance sequences for active surveillance of prostate cancer. The study included 530 men with an average age of 66, who were under surveillance for prostate cancer. We have used multiparametric magnetic resonance imaging with subsequent transperineal biopsy (TPB) to verify the imaging findings.

resultsWe have observed a level of agreement of 67.30% between the apparent diffusion coefficient (ADC) maps, other magnetic resonance sequences, and the biopsy results. The sensitivity of the apparent diffusion coefficient is 97.14%, and the specificity is 37.50%. According to our data, apparent diffusion coefficient is the most accurate sequence, followed by diffusion imaging in prostate cancer detection.

conclusionsBased on our findings we advocate that the apparent diffusion coefficient should be included as an essential part of magnetic resonance scanning protocols for prostate cancer in at least bi-parametric settings. The best option will be apparent diffusion coefficient combined with diffusion imaging and T2 sequences. Further large-scale prospective controlled studies are required to define the precise role of multiparametric and bi-parametric magnetic resonance in the active surveillance of prostate cancer.

Indexed as

imagingmp-MRIprostate cancerscreeningsurveillance

Identifiers

PMID36831471
PMCPMC9953850

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.