Evidence map›Paper›PMID 36831439›Full record

ReviewCancers2023

Oral Human Papillomavirus Benign Lesions and HPV-Related Cancer in Healthy Children: A Systematic Review.

Federica Di Spirito, Giuseppe Pantaleo, Maria Pia Di Palo, Alessandra Amato, Annunziata Raimondo, Massimo Amato

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  14. Comprehensive Analysis ofArchives of Razi Institute · 2024
    Review
  15. Article
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  17. Review
  18. Review
  19. Article
  20. Viral Infections of the Oral Cavity in Children.Children (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Federica Di SpiritoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0002-5458-6559
Giuseppe PantaleoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.
Maria Pia Di PaloDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0002-5443-8185
Alessandra AmatoDepartment of Neuroscience, Reproductive Science and Dentistry, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-8159-9785
Annunziata RaimondoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0002-0849-715X
Massimo AmatoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84084 Salerno, Italy.
University of Salerno · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present systematic review aimed to assess the prevalence of oral HPV-related lesions, categorized as benign (verruca vulgaris "VV", squamous cell papilloma "SP", condyloma acuminata "CA", and focal epithelial hyperplasia "FEH") and malignant (oral squamous cell carcinoma "OSCC"), in descending order of occurrence in pediatric subjects (≤18 years of age). The secondary objectives were to evaluate the frequency and types of oral lesions described in relation to HPV genotypes and the HPV vaccine type (if any). The study protocol, compliant with the PRISMA statement, was registered at PROSPERO (CRD42022352268). Data from 60 studies, of which quality was assessed using the ROBINS-I tool, were independently extracted and synthesized. Along with seven poorly described benign HPV-related oral lesions that could not be categorized, a total of 146 HPV-related oral lesions, namely 47.26% (

Indexed as

adolescentchildchildrencondyloma acuminatafocal epithelial hyperplasiaHPVhuman papillomavirusinfantoral lesionsoral manifestationsoral signsoral squamous cell carcinomapediatricsquamous cell papillomateenagerverruca vulgarisyoung

Identifiers

PMID36831439
PMCPMC9954073
OpenAlexW4319785986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.