Evidence map›Paper›PMID 36831381›Full record

ArticleCancers2023

Increased Expression Levels of Netrin-1 in Visceral Adipose Tissue during Obesity Favour Colon Cancer Cell Migration.

Amaia Mentxaka, Javier Gómez-Ambrosi, Gabriela Neira, Beatriz Ramírez, Sara Becerril, Amaia Rodríguez, Víctor Valentí, Rafael Moncada, Jorge Baixauli, María A Burrell and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Amaia MentxakaMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-6409-7513
Javier Gómez-AmbrosiMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5601-1604
Gabriela NeiraMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-3826-6579
Beatriz RamírezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Sara BecerrilMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3441-1970
Amaia RodríguezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-2180-461X
Víctor ValentíCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 31008 Pamplona, Spain.
Rafael MoncadaCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 31008 Pamplona, Spain.
Jorge BaixauliDepartment of Surgery, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-0667-7827
María A BurrellDepartment of Histology and Pathology, Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8018-764X
Camilo SilvaCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 31008 Pamplona, Spain.
Vasco ClaroSchool of Cardiovascular & Metabolic Medicine and Sciences, British Heart Foundation Centre of Research Excellence, King's College London, London SE1 9NH, UK.
Albert FerroSchool of Cardiovascular & Metabolic Medicine and Sciences, British Heart Foundation Centre of Research Excellence, King's College London, London SE1 9NH, UK.ORCID 0000-0002-5486-9145
Victoria CatalánMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-7513-7509
Gema FrühbeckMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8305-7154
Instituto de Salud Carlos III · ESKing's College London · GBClinica Universidad de Navarra · ESUniversidad de Navarra · ES

Funding

British Heart Foundation FS/18/69/33884
6 · The paper itself

Abstract

Netrin (NTN)-1, an extracellular matrix protein with a crucial role in inflammation, is dysregulated during obesity (OB) and influences colon cancer (CC) progression. To decipher the mechanisms underlying CC development during obesity, we examined the expression of

Indexed as

adipose tissuecell migrationcolon cancerDCCinflammationNEO-1NTN-1obesityUNC5B

Identifiers

PMID36831381
PMCPMC9953821
OpenAlexW4319439959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.