Evidence map›Paper›PMID 36831236›Full record

ArticleCells2023

Role of Cholesterol 25-Hydroxylase (Ch25h) in Mediating Innate Immune Responses to

Soo Jung Cho, Alexander Pronko, Jianjun Yang, Kassandra Pagan, Heather Stout-Delgado

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Soo Jung ChoWeill Cornell Medicine, New York, NY 10021, USA.ORCID 0000-0003-0759-7295
Alexander PronkoWeill Cornell Medicine, New York, NY 10021, USA.
Jianjun YangWeill Cornell Medicine, New York, NY 10021, USA.
Kassandra PaganWeill Cornell Medicine, New York, NY 10021, USA.ORCID 0000-0002-4971-1773
Heather Stout-DelgadoWeill Cornell Medicine, New York, NY 10021, USA.ORCID 0000-0002-2387-6924
Cornell University · US

Funding

Impact of Heightened UPR Activation on Inflammasome Responses to Influenza and Secondary Streptococcus pneumoniae Infection in Aged LungR01AG056699 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI STOUT DELGADO, HEATHER WINONA · 2018 to 2022
$2.6M
Impact of Heightened ER Stress on NLRP3 Activation in Aged Lung during InfectionR01AG052530 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI STOUT DELGADO, HEATHER WINONA · 2017 to 2021
$2.1M
GLUT1-dependent glycolysis regulates age-susceptible lung fibrosisK08HL138285 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHO, SOO JUNG · 2017 to 2021
$829k
NHLBI NIH HHS K08 HL138285NIA NIH HHS R01 AG052530NIA NIH HHS R01 AG056699
6 · The paper itself

Abstract

Alveolar macrophages (AM) are long-lived tissue-resident innate immune cells of the airways. AM are key effectors of recognition, initiation, and resolution of the host defense against microbes and play an essential role in mediating host responses to

Indexed as

LungPneumococcal InfectionsSteroid HydroxylasesAnimalsCytokinesImmunity, InnateMiceStreptococcus pneumoniaecholesterol 25-hydroxylaseCytokinesSteroid Hydroxylasesalveolar macrophageCh25hStreptococcus pneumoniae

Identifiers

PMID36831236
PMCPMC9953875
OpenAlexW4319968867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.