Evidence map›Paper›PMID 36830901›Full record

ArticleBiomedicines2023

Relationship between Novel Elastography Techniques and Renal Fibrosis-Preliminary Experience in Patients with Chronic Glomerulonephritis.

Felix-Mihai Maralescu, Adrian Vaduva, Adalbert Schiller, Ligia Petrica, Ioan Sporea, Alina Popescu, Roxana Sirli, Alis Dema, Madalina Bodea, Iulia Grosu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 15 citations in OpenAlex.

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  13. Noninvasive assessment of pediatric glomerular disease: multimodal ultrasound.Quantitative imaging in medicine and surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Felix-Mihai MaralescuDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-8273-4766
Adrian VaduvaCounty Emergency Hospital, L. Rebreanu Street, Nr. 156, 300723 Timisoara, Romania.ORCID 0000-0001-9261-5309
Adalbert SchillerDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Ligia PetricaDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-3138-3051
Ioan SporeaCounty Emergency Hospital, L. Rebreanu Street, Nr. 156, 300723 Timisoara, Romania.
Alina PopescuCounty Emergency Hospital, L. Rebreanu Street, Nr. 156, 300723 Timisoara, Romania.
Roxana SirliCounty Emergency Hospital, L. Rebreanu Street, Nr. 156, 300723 Timisoara, Romania.
Alis DemaCounty Emergency Hospital, L. Rebreanu Street, Nr. 156, 300723 Timisoara, Romania.ORCID 0000-0003-0767-2718
Madalina BodeaDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Iulia GrosuDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Flaviu BobDivision of Nephrology, Department of Internal Medicine II, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA renal biopsy represents the gold standard in the diagnosis, prognosis, and management of patients with glomerulonephritis. So far, non-invasive elastographic techniques have not confirmed their utility in replacing a biopsy; however, the new and improved software from Hologic Supersonic Mach 30 is a promising method for assessing the renal tissue's stiffness and viscosity. We investigated whether this elastography technique could reveal renal tissue fibrosis in patients with chronic glomerulonephritis. MATERIALS AND

methodsTwo-dimensional-shear wave elastography (SWE) PLUS and viscosity plane-wave ultrasound (Vi PLUS) assessments were performed in 40 patients with chronic glomerulopathies before being referred for a renal biopsy. For each kidney, the mean values of five stiffness and viscosity measures were compared with the demographic, biological, and histopathological parameters of the patients.

resultsIn total, 26 men and 14 women with a mean age of 52.35 ± 15.54 years, a mean estimated glomerular filtration rate (eGFR) of 53.8 ± 35.49 mL/min/1.73m

conclusionOur findings indicate that this novel elastography method can distinguish between individuals with different stages of renal fibrosis, correlate with the renal function and inflammation, and are easy to use and reproducible, but further research is needed for them to be employed routinely in clinical practice.

Indexed as

fibrosisinflammationrenal biopsystiffnessviscosity

Identifiers

PMID36830901
PMCPMC9953735
OpenAlexW4318208190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.