ArticleBiomedicines2023
The Cerebellum Gets Social: Evidence from an Exploratory Study of Cerebellar, Neurodevelopmental, and Psychiatric Disorders.
Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Unveiling the role of cerebellar alterations in the autonomic nervous system: a systematic review of autonomic dysfunction in spinocerebellar ataxias.Journal of neurology · 2023Pooled it
- Large-Scale Cerebellar-Cerebral Network Alterations Underlying Impaired Social Predictive Processing in Cerebellar Neurodegeneration.Cerebellum (London, England) · 2026Article
- Prevalence and risk factors of bipolar disorder in central nervous system autoimmune demyelinating diseases.BMC psychiatry · 2026Article
- Opposing Changes in Cerebellar Dopaminergic Genes Co-Expression Networks in Different Models of Neurodevelopmental Disorders.International journal of molecular sciences · 2026Article
- False Beliefs, True Deficits: Investigating Social Cognition in Friedreich Ataxia.Cerebellum (London, England) · 2025Article
- Functional recruitment and connectivity of the cerebellum is associated with the emergence of Theory of Mind in early childhood.Nature communications · 2025Article
- Contributions of the posterior cerebellum to mentalizing and social functioning: A transdiagnostic investigation.Psychological medicine · 2025Article
- The Cerebellar Role in Emotions at a Turning Point: Bibliometric Analysis and Collaboration Networks.Cerebellum (London, England) · 2025Review
- Neural basis of self-esteem: social cognitive and emotional regulation insights.Frontiers in neuroscience · 2025Article
- Consensus Paper: Cerebellum and Reward.Cerebellum (London, England) · 2024Review
- Cerebellar Neurostimulation for Boosting Social and Affective Functions: Implications for the Rehabilitation of Hereditary Ataxia Patients.Cerebellum (London, England) · 2024Review
- Fecal microbiota transplantation in a child with severe ASD comorbidities of gastrointestinal dysfunctions-a case report.Frontiers in psychiatry · 2023Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
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Abstract
Social prediction is a key feature of social cognition (SC), a function in which the modulating role of the cerebellum is recognized. Accordingly, cerebellar alterations are reported in cerebellar pathologies, neurodevelopmental disorders, and psychiatric conditions that show SC deficits. Nevertheless, to date, no study has directly compared populations representative of these three conditions with respect to SC and cerebellar alterations. Therefore, the present exploratory study aimed to compare the SC profiles of individuals with cerebellar neurodegenerative disorders (CB), autism (ASD), bipolar disorder type 2 (BD2), or healthy subjects (HS) using a battery of social tests requiring different degrees of prediction processing. The patterns of cerebellar gray matter (GM) alterations were compared among the groups using voxel-based morphometry. Compared to HS, the clinical groups showed common SC deficits in tasks involving a moderate to high level of prediction. The behavioral results of the clinical groups are consistent with the presence of overlapping GM reduction in cerebellar right Crus II, an area notably involved in complex social processing and prediction. Although exploratory and preliminary, these results deepen the cerebellar role in social prediction and highlight the transdiagnostic value of the cerebellum in social functioning and prediction in pathologies of different aetiologies, forecasting novel possibilities for shared interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.