Evidence map›Paper›PMID 36830773›Full record

ArticleBiomedicines2023

Difference in Methylation and Expression of Brain-Derived Neurotrophic Factor in Alzheimer's Disease and Mild Cognitive Impairment.

Katarina Kouter, Matea Nikolac Perkovic, Gordana Nedic Erjavec, Tina Milos, Lucija Tudor, Suzana Uzun, Ninoslav Mimica, Nela Pivac, Alja Videtic Paska

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Disruption of BDNF signalling in neuropathologies.Biochemical Society transactions · 2026
    Review
  2. BDNF-amyloid-Frontiers in molecular neuroscience · 2026
    Review
  3. Article
  4. International journal of molecular sciences · 2025
    Article
  5. Biomarkers of cognitive and memory decline in psychotropic drug users.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Katarina KouterInstitute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-1051-959X
Matea Nikolac PerkovicLaboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-3113-0778
Gordana Nedic ErjavecLaboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-0787-9340
Tina MilosLaboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.
Lucija TudorLaboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-9125-406X
Suzana UzunDepartment for Biological Psychiatry and Psychogeriatrics, University Psychiatric Hospital Vrapce, 10090 Zagreb, Croatia.
Ninoslav MimicaDepartment for Biological Psychiatry and Psychogeriatrics, University Psychiatric Hospital Vrapce, 10090 Zagreb, Croatia.ORCID 0000-0003-4552-0547
Nela PivacLaboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.
Alja Videtic PaskaInstitute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-1182-5417
Ruđer Bošković Institute · HRUniversity of Ljubljana · SIUniversity of Zagreb · HR

Funding

Slovenian Research Agency J3-9293
6 · The paper itself

Abstract

Due to the increasing number of progressive dementias in the population, numerous studies are being conducted that seek to determine risk factors, biomarkers and pathological mechanisms that could help to differentiate between normal symptoms of aging, mild cognitive impairment (MCI) and dementia. The aim of this study was to investigate the possible association of levels of

Indexed as

Alzheimer’s dementiaBDNFbrain-derived neurotrophic factorcatechol-o-methyltransferasecognitive impairmentCOMTdementiaDNA methylationepigeneticsgene expression

Identifiers

PMID36830773
PMCPMC9953261
OpenAlexW4316804877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.