Evidence map›Paper›PMID 36830738›Full record

ArticleBiomolecules2023

NOD2 Agonism Counter-Regulates Human Type 2 T Cell Functions in Peripheral Blood Mononuclear Cell Cultures: Implications for Atopic Dermatitis.

Vladimir-Andrey Gimenez-Rivera, Harshita Patel, Franck P Dupuy, Zoulfia Allakhverdi, Charlie Bouchard, Joaquín Madrenas, Robert Bissonnette, Ciriaco A Piccirillo, Carolyn Jack

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Vladimir-Andrey Gimenez-RiveraInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.ORCID 0000-0001-5055-208X
Harshita PatelInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.
Franck P DupuyInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.
Zoulfia AllakhverdiInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.ORCID 0000-0001-5194-2792
Charlie BouchardInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.ORCID 0000-0003-2430-0035
Joaquín MadrenasDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Robert BissonnetteInnovaderm Research, Montréal, QC H2X 2V1, Canada.
Ciriaco A PiccirilloDepartment of Microbiology and Immunology, McGill University, Montréal, QC H3A 2B4, Canada.
Carolyn JackInfectious Diseases and Immunity in Global Health, Center for Translational Biology, The Research Institute of the McGill University Health Center, Montréal, QC H4A 3J1, Canada.ORCID 0000-0002-0376-3324
McGill University Health Centre · CAInnovaderm (Canada) · CAMcGill University · CAUniversity of California, Los Angeles · US

Funding

Canadian Dermatology Foundation WCH Ref [412-001], CDF Team Grant for Canadian Atopic Dermatitis Cohort for Translational Immunology and Imaging (CACTI)CIHR MOP 142257
6 · The paper itself

Abstract

Atopic dermatitis (AD) is known as a skin disease; however, T cell immunopathology found in blood is associated with its severity. Skin

Indexed as

Dermatitis, AtopicAdultBiomarkersChemokinesCytokinesHumansInterleukin-13Leukocytes, MononuclearNod2 Signaling Adaptor ProteinStaphylococcus aureusBiomarkersChemokinesCytokinesInterleukin-13NOD2 protein, humanNod2 Signaling Adaptor Proteinatopic dermatitisGATA Binding Protein 3interleukin-13nucleotide-binding oligomerization domain-containing protein 2peptidoglycansignal transducer of activated T cellsStaphylococcus aureusStaphylococcus aureus enterotoxin BT helper 2 and cytotoxic type 2 T cellsthymic stromal lymphopoietinthymus and activation-related chemokinetype 2 cytokines

Identifiers

PMID36830738
PMCPMC9953199
OpenAlexW4321093730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.