Evidence map›Paper›PMID 36830693›Full record

ArticleBiomolecules2023

CRISPR/Cas9-Induced Knockout of

Sarithaa Sellaththurai, Sumi Jung, Myoung-Jin Kim, Kishanthini Nadarajapillai, Subothini Ganeshalingam, Joon Bum Jeong, Jehee Lee

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Suppressors of cGAS-STING are downregulated during fin-limb regeneration and aging in aquatic vertebrates.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sarithaa SellaththuraiDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Sumi JungDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Myoung-Jin KimNakdonggang National Institute of Biological Resources, Sangju 37242, Republic of Korea.
Kishanthini NadarajapillaiDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Subothini GaneshalingamDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Joon Bum JeongDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Jehee LeeDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.ORCID 0000-0001-9144-3648
Jeju National University · KRNational Institute of Biological Resources · KR

Funding

Ministry of Education 2019R1A6A1A03033553Ministry of Oceans and Fisheries 20220570
6 · The paper itself

Abstract

Stimulator of interferon genes (STING) is an adapter protein that is activated when cyclic dinucleotides (CDNs) are present. CDNs originate from the cytosolic DNA of both pathogens and hosts. STING activation promotes efficient immune responses against viral infections; however, its impact in bacterial infections is unclear. In this study, we investigated the role of Sting in bacterial infections by successfully creating a

Indexed as

Bacterial InfectionsZebrafishAnimalsCRISPR-Cas SystemsImmunity, InnateLipopolysaccharidesNF-kappa BNucleotidyltransferasesLipopolysaccharidesNF-kappa BNucleotidyltransferasesCRISPR/Cas9Edwardsiella piscicidastimulator of interferon genezebrafish

Identifiers

PMID36830693
PMCPMC9953276
OpenAlexW4319595805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.