Evidence map›Paper›PMID 36830602›Full record

ArticleBiomolecules2023

Ultramicronized

Alessandra Toti, Laura Micheli, Elena Lucarini, Valentina Ferrara, Clara Ciampi, Francesco Margiotta, Paola Failli, Chiara Gomiero, Marco Pallecchi, Gianluca Bartolucci and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. An olive oil-derived NAE mixture (OlaliamidBMC veterinary research · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alessandra TotiDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0002-8435-6017
Laura MicheliDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0001-8834-5801
Elena LucariniDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0002-3459-2660
Valentina FerraraDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.
Clara CiampiDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0002-6455-2723
Francesco MargiottaDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0002-4172-2478
Paola FailliDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.
Chiara GomieroEpitech Group SpA, Via Luigi Einaudi 13, 35030 Padua, Italy.ORCID 0000-0003-4853-6640
Marco PallecchiDepartment of Chemistry, University of Florence, Via Ugo Schiff 6, 50019 Florence, Italy.ORCID 0000-0002-0057-6531
Gianluca BartolucciDepartment of Chemistry, University of Florence, Via Ugo Schiff 6, 50019 Florence, Italy.ORCID 0000-0002-5631-8769
Carla GhelardiniDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.
Lorenzo Di Cesare MannelliDepartment of Neuroscience, Psychology, Drug Research and Child Health-NEUROFARBA-Pharmacology and Toxicology Section, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy.ORCID 0000-0001-8374-4432
University of Florence · IT

Funding

Italian Ministry of University and ResearchUniversity of Florence
6 · The paper itself

Abstract

Persistent pain can be managed with opioids, but their use is limited by the onset of tolerance. Ultramicronized

Indexed as

AstrocytesMorphineAmidesAnalgesics, OpioidDrug ToleranceEthanolaminesHumansMast CellsPainPalmitic AcidsAmidesAnalgesics, OpioidEthanolaminesMorphinepalmidrolPalmitic Acidscross-talkglial cellsmast cellmorphineN-palmitoylethanolaminetolerance

Identifiers

PMID36830602
PMCPMC9953591
OpenAlexW4318053875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.