Evidence map›Paper›PMID 36830333›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Treatment of Mouse Infants with Amoxicillin, but Not the Human Milk-Derived Antimicrobial HAMLET, Impairs Lung Th17 Responses.

Sudhanshu Shekhar, Navdeep Kaur Brar, Anders P Håkansson, Fernanda Cristina Petersen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sudhanshu ShekharInstitute of Oral Biology, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0003-3187-2496
Navdeep Kaur BrarInstitute of Oral Biology, University of Oslo, 0316 Oslo, Norway.
Anders P HåkanssonDivision of Experimental Infection Medicine, Department of Translational Medicine, Lund University, 21428 Malmö, Sweden.ORCID 0000-0002-2834-6009
Fernanda Cristina PetersenInstitute of Oral Biology, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0003-4649-247X
University of Oslo · NOLund University · SE

Funding

Olav Thon Foundation NAThe Research Council of Norway 273833 and 274867
6 · The paper itself

Abstract

Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of the treatment of mouse infants with amoxicillin and the human milk-derived antimicrobial HAMLET (human alpha-lactalbumin made lethal to tumor cells) on T cell responses to

Indexed as

amoxicillinHAMLETinfantslungsTh17 immunity

Identifiers

PMID36830333
PMCPMC9952748
OpenAlexW4321457440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.