Evidence map›Paper›PMID 36830314›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Carbapenem-Resistant

Youssef Madney, Shaimaa Aboubakr, Reham Khedr, Hanafy Hafez, Naglaa Ahmed, Khaled Elsheshtawy, Mervat Elanany, Abdelhamid Salahelden, Lobna Shalaby, Ola Galal Behairy

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Whole Genome Sequencing ofAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Infections withJournal of clinical medicine · 2024
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Youssef MadneyDepartment of Pediatric Oncology, National Cancer Institute, Cairo University, Cairo 12613, Egypt.ORCID 0000-0003-0511-1562
Shaimaa AboubakrDepartment of Paediatrics, Faculty Of Medicine, Benha University, Benha 15881, Egypt.
Reham KhedrDepartment of Pediatric Oncology, National Cancer Institute, Cairo University, Cairo 12613, Egypt.ORCID 0000-0001-5355-8225
Hanafy HafezDepartment of Pediatric Oncology, National Cancer Institute, Cairo University, Cairo 12613, Egypt.
Naglaa AhmedDepartment of Clinical Pharmacy, Children's Cancer Hospital Egypt, Cairo 57357, Egypt.ORCID 0000-0002-7438-9771
Khaled ElsheshtawyDepartment of Clinical Research, Children's Cancer Hospital Egypt, Cairo 57357, Egypt.
Mervat ElananyDepartment of Clinical Microbiology, Faculty Of Medicine, Cairo University and Children's Cancer Hospital Egypt, Cairo 57357, Egypt.
Abdelhamid SalaheldenDepartment of Paediatrics, Faculty Of Medicine, Benha University, Benha 15881, Egypt.
Lobna ShalabyDepartment of Pediatric Oncology, National Cancer Institute, Cairo University, Cairo 12613, Egypt.
Ola Galal BehairyDepartment of Paediatrics, Faculty Of Medicine, Benha University, Benha 15881, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) is an important emerging threat among pediatric cancer patients, with a high mortality rate. This retrospective study included all pediatric cancer patients with (CRE) bloodstream infections (BSIs) at a children's cancer hospital in Egypt (2013-2017). Two hundred and fifty-four pediatric cancer patients with CRE BSI were identified; 74% had hematological malignancies, and 26% had solid tumors. Acute myeloid leukemia was the most common hematological malignancy (50%). The main clinical features for acquiring CRE-BSI were previous antibiotics exposure (90%), profound neutropenia (84%), prolonged steroid use (45%), previous colonization with a resistant pathogen (35%), ICU admission within 90 days (28%), and central venous catheter use (24%).

Indexed as

cancercarbapenem-resistant Enterobacteriaceae (CRE)childrenpredictors of mortality

Identifiers

PMID36830314
PMCPMC9952844

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.