Evidence map›Paper›PMID 36830285›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Artificial Intelligence Can Guide Antibiotic Choice in Recurrent UTIs and Become an Important Aid to Improve Antimicrobial Stewardship.

Tommaso Cai, Umberto Anceschi, Francesco Prata, Lucia Collini, Anna Brugnolli, Serena Migno, Michele Rizzo, Giovanni Liguori, Luca Gallelli, Florian M E Wagenlehner and 4 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Artificial intelligence in antimicrobial stewardship: a systematic review and meta-analysis of predictive performance and diagnostic accuracy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  3. Evolution of technology and disparities in antimicrobial stewardship: a narrative review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Tommaso CaiDepartment of Urology, Santa Chiara Regional Hospital, 38123 Trento, Italy.ORCID 0000-0002-7234-3526
Umberto AnceschiIRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.
Francesco PrataDepartment of Urology, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Lucia ColliniDepartment of Microbiology, Santa Chiara Regional Hospital, 38123 Trento, Italy.
Anna BrugnolliCentre of Higher Education for Health Sciences, 38122 Trento, Italy.ORCID 0000-0002-7502-4563
Serena MignoDepartment of Gynecology and Obstetrics, Santa Chiara Regional Hospital, 38123 Trento, Italy.
Michele RizzoDepartment of Urology, University of Trieste, 34127 Trieste, Italy.
Giovanni LiguoriDepartment of Urology, University of Trieste, 34127 Trieste, Italy.
Luca GallelliDepartment of Health Science, School of Medicine, University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-0858-7902
Florian M E WagenlehnerClinic for Urology, Pediatric Urology and Andrology, Justus Liebig University, 35390 Giessen, Germany.ORCID 0000-0002-2909-0797
Truls E Bjerklund JohansenInstitute of Clinical Medicine, University of Oslo, 0315 Oslo, Norway.ORCID 0000-0003-3490-6460
Luca MontanariDepartment of Medicine (DAME), Infectious Diseases Clinic, University of Udine, 33100 Udine, Italy.
Alessandro PalmieriDepartment of Urology, University of Naples Federico II, 80138 Naples, Italy.
Carlo TasciniDepartment of Medicine (DAME), Infectious Diseases Clinic, University of Udine, 33100 Udine, Italy.ORCID 0000-0001-9625-6024
Ospedale Santa Chiara · ITUniversity of Trieste · ITUniversity of Udine · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITJustus-Liebig-Universität Gießen · DEOslo University Hospital · NOUniversità Campus Bio-Medico · ITUniversity of Naples Federico II · ITUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA correct approach to recurrent urinary tract infections (rUTIs) is an important pillar of antimicrobial stewardship. We aim to define an Artificial Neural Network (ANN) for predicting the clinical efficacy of the empiric antimicrobial treatment in women with rUTIs.

methodsWe extracted clinical and microbiological data from 1043 women. We trained an ANN on 725 patients and validated it on 318.

resultsThe ANN showed a sensitivity of 87.8% and specificity of 97.3% in predicting the clinical efficacy of empirical therapy. The previous use of fluoroquinolones (HR = 4.23;

conclusionsANNs seem to be an interesting tool to guide the antimicrobial choice in the management of rUTIs at the point of care.

Indexed as

antibiotic resistanceartificial intelligencerecurrenceurinary tract infection

Identifiers

PMID36830285
PMCPMC9952599
OpenAlexW4320492080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.