Evidence map›Paper›PMID 36830284›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Impact of Pharmacist-Led Multidisciplinary Team to Attain Targeted Vancomycin Area under the Curved Monitoring in a Tertiary Care Center in Thailand.

Kittiya Jantarathaneewat, Tuangrat Phodha, Kankanit Singhasenee, Panipak Katawethiwong, Nuntra Suwantarat, Bernard Camins, Thanawat Wongphan, Sasinuch Rutjanawech, Anucha Apisarnthanarak

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Kittiya JantarathaneewatCenter of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
Tuangrat PhodhaCenter of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
Kankanit SinghaseneePharmacy Unit, Thammasat University Hospital, Pathum Thani 12120, Thailand.
Panipak KatawethiwongPaholpolpayuhasena Hospital, Kanchanaburi 71000, Thailand.
Nuntra SuwantaratDivision of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand.
Bernard CaminsDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA.
Thanawat WongphanCenter of Excellence in Pharmacy Practice and Management Research, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
Sasinuch RutjanawechResearch Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand.
Anucha ApisarnthanarakResearch Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand.
Thammasat University · THIcahn School of Medicine at Mount Sinai · USPrapokklao Hospital · THThammasat University Hospital · TH

Funding

Faculty of Pharmacy, Thammasat University under the Specialized Research Grant Pharm TU-S 3/2020Thailand Science Research and Innovation Fundamental Fund fiscal year 2023
6 · The paper itself

Abstract

Vancomycin Area Under the Curve (AUC) monitoring has been recommended to ensure successful clinical outcomes and minimize the risk of nephrotoxicity, rather than traditional trough concentration. However, vancomycin AUC monitoring by a pharmacist-led multidisciplinary team (PMT) has not been well established in Southeast Asia. This study was conducted at Thammasat University Hospital. Adult patients aged ≥ 18 years who were admitted and received intravenous vancomycin ≥48 h were included. The pre-PMT period (April 2020-September 2020) was defined as a period using traditional trough concentration, while the post-PMT period (October 2020-March 2021) was defined as a period using PMT to monitor vancomycin AUC. The primary outcome was the rate of achievement of the therapeutic target of an AUC/MIC ratio of 400-600. There was a significantly higher rate of achievement of therapeutic target vancomycin AUC during post-PMT period (66.7% vs. 34.3%,

Indexed as

area under the curvepharmacist-led interventiontherapeutic drug monitoringvancomycin

Identifiers

PMID36830284
PMCPMC9952732
OpenAlexW4320492052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.