Evidence map›Paper›PMID 36830227›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Influence of Skin Commensals on Therapeutic Outcomes of Surgically Debrided Diabetic Foot Infections-A Large Retrospective Comparative Study.

Ilker Uçkay, Dan Lebowitz, Benjamin Kressmann, Benjamin A Lipsky, Karim Gariani

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilker UçkayInfectiology, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland.
Dan LebowitzService of Infectious Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Benjamin KressmannService of Infectious Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Benjamin A LipskyService of Infectious Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Karim GarianiService of Infectious Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.ORCID 0000-0001-8089-4785

Funding

University Hospital of Geneva n.a.
6 · The paper itself

Abstract

In diabetic foot infections (DFI), the clinical virulence of skin commensals are generally presumed to be low. In this single-center study, we divided the wound isolates into two groups: skin commensals (coagulase-negative staphylococci, micrococci, corynebacteria, cutibacteria) and pathogenic pathogens, and followed the patients for ≥ 6 months. In this retrospective study among 1018 DFI episodes (392 [39%] with osteomyelitis), we identified skin commensals as the sole culture isolates (without accompanying pathogenic pathogens) in 54 cases (5%). After treatment (antibiotic therapy [median of 20 days], hyperbaric oxygen in 98 cases [10%]), 251 episodes (25%) were clinical failures. Group comparisons between those growing only skin commensals and controls found no difference in clinical failure (17% vs. 24 %,

Indexed as

antibiotic therapyassociations with treatment failurediabetic foot infectionsnon-beta-lactam antibioticsskin commensalstreatment failures

Identifiers

PMID36830227
PMCPMC9952192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.