Evidence map›Paper›PMID 36830219›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Synthesis, Characterization, Cytotoxicity Analysis and Evaluation of Novel Heterocyclic Derivatives of Benzamidine against Periodontal Disease Triggering Bacteria.

Ramasamy Kavitha, Mohammad Auwal Sa'ad, Shivkanya Fuloria, Neeraj Kumar Fuloria, Manickam Ravichandran, Pattabhiraman Lalitha

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramasamy KavithaDepartment of Biotechnology, Faculty of Applied Science, AIMST University, Bedong 08100, Kedah, Malaysia.
Mohammad Auwal Sa'adDepartment of Biotechnology, Faculty of Applied Science, AIMST University, Bedong 08100, Kedah, Malaysia.
Shivkanya FuloriaCentre of Excellence for Biomaterials Engineering, Faculty of Pharmacy, AIMST University, Bedong 08100, Kedah, Malaysia.
Neeraj Kumar FuloriaCentre of Excellence for Biomaterials Engineering, Faculty of Pharmacy, AIMST University, Bedong 08100, Kedah, Malaysia.
Manickam RavichandranDepartment of Biotechnology, Faculty of Applied Science, AIMST University, Bedong 08100, Kedah, Malaysia.ORCID 0000-0001-5321-1344
Pattabhiraman LalithaDepartment of Biochemistry, Faculty of Medicine, AIMST University, Bedong 08100, Kedah, Malaysia.

Funding

Ministry of Higher Education FRGS/1/2018/SKK14/AIMST/01/1
6 · The paper itself

Abstract

Periodontal disease (PD) is multifactorial oral disease that damages tooth-supporting tissue. PD treatment includes proper oral hygiene, deep cleaning, antibiotics therapy, and surgery. Despite the availability of basic treatments, some of these are rendered undesirable in PD treatment due to side effects and expense. Therefore, the aim of the present study is to develop novel molecules to combat the PD triggering pathogens. The study involved the synthesis of 4-((5-(substituted-phenyl)-1,3,4-oxadiazol-2-yl)methoxy)benzamidine (

Indexed as

antibacterialbenzamidineheterocyclicsperiodontal diseaseperiodontitis

Identifiers

PMID36830219
PMCPMC9952644

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.