ArticleAntibiotics (Basel, Switzerland)2023
Antimicrobial Activities and Mode of Flavonoid Actions.
Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
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- Mechanisms of Bacterial Resistance and Innovative Strategies to Overcome Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2026Review
- Solvent dependent bioactivity and spectroscopic characterization of neovestitol from Nigerian propolis using experimental and computational methods.Scientific reports · 2026Article
- Integrated computational and experimental evaluation of natural products targeting PGM/AlgC and HisIE in multidrug-resistant respiratory pathogens.Frontiers in microbiology · 2026Article
- Attenuation ofAntibiotics (Basel, Switzerland) · 2025Article
- In vitro phytochemical and biological evaluation of hydroethanolic extract of Anchomanes difformis In Togo.Scientific reports · 2025Article
- Phytochemical and antimicrobial properties of Morus nigra and Morus alba grown in Fujairah, United Arab Emirates.Scientific reports · 2025Article
- Antimicrobial activity of new glycoside derivatives of chloroflavones obtained by fungal biotransformation.Scientific reports · 2025Article
- Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Impact of the flavonoid-induced intestinal microbiota modulation on global energy metabolism: implication for obesity.Frontiers in nutrition · 2025Review
- Molecular detection ofIn silico pharmacology · 2025Article
- The Influence of Flavonoids with -Br, -Cl Atoms and -NOInternational journal of molecular sciences · 2024Article
- An Eco-Friendly Method to Synthesize Potent Antimicrobial Tricyclic Flavonoids.Antibiotics (Basel, Switzerland) · 2024Article
- Antimicrobial Properties of Flavonoid Derivatives with Bromine, Chlorine, and Nitro Group Obtained by Chemical Synthesis and Biotransformation Studies.International journal of molecular sciences · 2024Article
- Nutraceutical and Medicinal Importance of Marine Molluscs.Marine drugs · 2024Review
- Exploring the Wound Healing Potential of aPharmaceutics · 2024Article
- Using Subcritical Water to Obtain Polyphenol-Rich Extracts with Antimicrobial Properties.Antibiotics (Basel, Switzerland) · 2024Review
- Antibacterial Activity and Mechanisms of Plant Flavonoids against Gram-Negative Bacteria Based on the Antibacterial Statistical Model.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Chitosan dual gel-like functionalized with flavonoid extract and cinnamaldehyde oil using dual cross-linking agents: Characterization, antioxidant, and antimicrobial effects.Current research in food science · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The emergence of antibiotics-resistant bacteria has been a serious concern for medical professionals over the last decade. Therefore, developing new and effective antimicrobials with modified or different modes of action is a continuing imperative. In this context, our study focuses on evaluating the antimicrobial activity of different chemically synthesized flavonoids (FLAV) to guide the chemical synthesis of effective antimicrobial molecules. A set of 12 synthesized molecules (4 chalcones, 4 flavones and 4 flavanones), bearing substitutions with chlorine and bromine groups at the C6' position and methoxy group at the C4' position of the B-ring were evaluated for antimicrobial activity toward 9 strains of Gram-positive and Gram-negative bacteria and 3 fungal strains. Our findings showed that most tested FLAV exhibited moderate to high antibacterial activity, particularly against
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.