Evidence map›Paper›PMID 36830052›Full record

ArticleAntioxidants (Basel, Switzerland)2023

CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD

Pamela Becherini, Debora Soncini, Silvia Ravera, Elisa Gelli, Claudia Martinuzzi, Giulia Giorgetti, Antonia Cagnetta, Fabio Guolo, Federico Ivaldi, Maurizio Miglino and 13 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The role of NADFrontiers in oncology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
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  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 6 institutions in 1 country.

Pamela BecheriniClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Debora SonciniClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Silvia RaveraDepartment of Experimental Medicine (DIMES), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0002-0803-1042
Elisa GelliClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Claudia MartinuzziIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0001-7388-188X
Giulia GiorgettiClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Antonia CagnettaClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Fabio GuoloClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0003-3166-6078
Federico IvaldiDepartment of Internal Medicine (DiMI), University of Genoa, 16126 Genoa, Italy.
Maurizio MiglinoClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Sara AquinoHematology and Hematopoietic Stem Cell Transplantation Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Katia TodoertiPathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori di Milan, 20133 Milano, Italy.
Antonino NeriScientific Directorate, Azienda USL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Andrea BenziDepartment of Experimental Medicine (DIMES), University of Genoa, 16126 Genoa, Italy.
Mario PassalacquaDepartment of Experimental Medicine (DIMES), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0003-2779-6259
Alessio NencioniIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Ida PerrottaDepartment of Biology, Ecology and Earth Sciences, Centre for Microscopy and Microanalysis (CM2), University of Calabria, Arcavacata di Rende, 87036 Cosenza, Italy.
Maria Eugenia Gallo CantafioDepartment of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Nicola AmodioDepartment of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Antonio De FloraDepartment of Experimental Medicine (DIMES), University of Genoa, 16126 Genoa, Italy.
Santina BruzzoneDepartment of Experimental Medicine (DIMES), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0003-2034-3716
Roberto M LemoliClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.
Michele CeaClinic of Hematology, Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0002-1530-6729
University of Genoa · ITOspedale Policlinico San Martino · ITMagna Graecia University · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITUniversity of Calabria · IT

Funding

Italian Association for Cancer Research 21552Italian Association for Cancer Research 2328Italian Association for Cancer Research 24449Italian Ministry of Health GR-2016-02361523
6 · The paper itself

Abstract

Cancer cells fuel growth and energy demands by increasing their NAD

Indexed as

cancer metabolismmitochondrial disfunctionmultiple myelomaNAD+ biosynthetic pathwayNAD+-lowering agentsoxidative stress

Identifiers

PMID36830052
PMCPMC9952390
OpenAlexW4321105713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.