Evidence map›Paper›PMID 36830034›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Effect-Directed, Chemical and Taxonomic Profiling of Peppermint Proprietary Varieties and Corresponding Leaf Extracts.

Antonio M Inarejos-Garcia, Julia Heil, Patricia Martorell, Beatriz Álvarez, Silvia Llopis, Ines Helbig, Jie Liu, Bryon Quebbeman, Tim Nemeth, Deven Holmgren and 1 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Phytochemical and Bioactivity Studies onAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonio M Inarejos-GarciaDepartment of Functional Extracts, ADM Valencia, 46740 Carcaixent, Spain.ORCID 0000-0002-4869-6188
Julia HeilChair of Food Science, Institute of Nutritional Science, and TransMIT Center for Effect-Directed Analysis, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.
Patricia MartorellArcher Daniels Midland, Nutrition, Health&Wellness, ADM® Biopolis S.L. Parc Cintífic Universitat de València, Calle Catedrático Agustín Escardino Benlloch, 46980 Paterna, Spain.ORCID 0000-0001-5689-8399
Beatriz ÁlvarezArcher Daniels Midland, Nutrition, Health&Wellness, ADM® Biopolis S.L. Parc Cintífic Universitat de València, Calle Catedrático Agustín Escardino Benlloch, 46980 Paterna, Spain.
Silvia LlopisArcher Daniels Midland, Nutrition, Health&Wellness, ADM® Biopolis S.L. Parc Cintífic Universitat de València, Calle Catedrático Agustín Escardino Benlloch, 46980 Paterna, Spain.
Ines HelbigDepartment of Science & Technology, ADM Wild Europe, 13597 Berlin, Germany.
Jie LiuDepartment of Genetics, ADM Wild, Chicago, IL 60601, USA.
Bryon QuebbemanDepartment of Genetics, ADM Wild, Chicago, IL 60601, USA.
Tim NemethDepartment of Genetics, ADM Wild, Chicago, IL 60601, USA.
Deven HolmgrenDepartment of Genetics, ADM Wild, Chicago, IL 60601, USA.
Gertrud E MorlockChair of Food Science, Institute of Nutritional Science, and TransMIT Center for Effect-Directed Analysis, Justus Liebig University Giessen, Heinrich-Buff-Ring 26-32, 35392 Giessen, Germany.ORCID 0000-0001-9406-0351

Funding

Deutsche Forschungsgemeinschaft INST 162/471-1 FUGGDeutsche Forschungsgemeinschaft INST 162/536-1 FUGG
6 · The paper itself

Abstract

During the development of novel, standardized peppermint extracts targeting functional applications, it is critical to adequately characterize raw material plant sources to assure quality and consistency of the end-product. This study aimed to characterize existing and proprietary, newly bred varieties of peppermint and their corresponding aqueous extract products. Taxonomy was confirmed through genetic authenticity assessment. Non-target effect-directed profiling was developed using high-performance thin-layer chromatography-multi-imaging-effect-directed assays (HPTLC-UV/Vis/FLD-EDA). Results demonstrated substantial differences in compounds associated with functional attributes, notably antioxidant potential, between the peppermint samples. Further chemical analysis by high-performance liquid chromatography-photodiode array/mass spectrometry detection (HPLC-PDA/MS) and headspace solid-phase microextraction-gas chromatography-flame ionization/MS detection (headspace SPME-GC-FID/MS) confirmed compositional differences. A broad variability in the contents of flavonoids and volatiles was observed. The peppermint samples were further screened for their antioxidant potential using the

Indexed as

antioxidantCaenorhabditis elegansflavonoidfunctional foodheadspace SPME–GC–FID/MShigh-performance thin-layer chromatographyHPLC–PDA/MSHPTLC–UV/Vis/FLD–EDAplanar bioassayplanar enzyme assay

Identifiers

PMID36830034
PMCPMC9952098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.