ArticleAntioxidants (Basel, Switzerland)2023
Cannabidiol (CBD) Supports the Honeybee Worker Organism by Activating the Antioxidant System.
Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- The Effect of Cannabidiol (CBD) on the Modulation of Proteolytic Activity on the Honey Bee Workers' Cuticle.Molecules (Basel, Switzerland) · 2026Article
- Article
- Fungal extracts influence lifespan and immune responses in the Carniolan honey bee (Apis mellifera carnica, Pollmann 1879).Scientific reports · 2026Article
- Analysis of Panels of Chemical Biomarkers in the Honeybee in Hemolymph and Fat Body in Response to Physiological and Environmental Factors.Metabolites · 2025Review
- The antioxidant system was unexpectedly strongly suppressed in apis mellifera worker bees emerged from larvae reared on combs adulterated with paraffin or stearin.Scientific reports · 2025Article
- Chemical Composition and Antioxidant Activity of Prokupac Grape Pomace Extract: Implications for Redox Modulation in Honey Bee Cells.Antioxidants (Basel, Switzerland) · 2025Article
- From Digestion to Detoxification: Exploring Plant Metabolite Impacts on Insect Enzyme Systems for Enhanced Pest Control.Insects · 2025Review
- Changes in the Activities of Antioxidant Enzymes in the Fat Body and Hemolymph ofAntioxidants (Basel, Switzerland) · 2025Article
- Workers ofAnimals : an open access journal from MDPI · 2023Article
- Effect of Rearing in Small-Cell Combs on Activities of Catalase and Superoxide Dismutase and Total Antioxidant Capacity in the Hemolymph ofAntioxidants (Basel, Switzerland) · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the experiment, we tested the effect of 30% CBD oil on the activity of the antioxidant system (superoxide dismutase, catalase, glutathione peroxidase, glutathione), the level of total antioxidant capacity, and the concentrations of ions (calcium, magnesium, and phosphorus) in honeybee workers in the hive test. For this purpose, we prepared hives containing all stages of the development of honey bees and started the experiment by adding 200 marked, one-day old bees to each colony (intended for hemolymph collection). In the test, we created three groups (two colonies per group): (1) Experimental with CBD oil mixed with sugar syrup (CSy); (2) experimental with CBD oil on textile strips (CSt); and (3) control with pure sugar syrup only (C). Every week, we collected hemolymph from the marked bees. In the experiment, all antioxidant enzyme activities were higher for the experimental groups CSy and CSt compared to group C. The highest concentrations/levels were obtained for the CSy group. Concentrations of calcium, magnesium, and phosphorus ions were also higher for the experimental groups compared to the C group (the highest concentration for the CSy group). We conclude that CBD oil positively contributes to stimulating the antioxidant system of honeybees.
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